Yazar "Pehlivan, Sacide" için listeleme
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Is there any Association between the Functional Variants of the NOS3 Gene and Psoriasis?
Pehlivan, Sacide; İnalöz, Hüseyin Serhat; Nursal, Ayşe Feyda; Gülel, Aslıhan; Pehlivan, Mustafa (2018)Introduction: Psoriasis (Ps) is a chronic, immune-mediated inflammatory skin disorder with an incompletely understood etiology. The aim of this study was to investigate the relationship between the suspectibility to Ps and ... -
Medication-related osteonecrosis of the jaw (MRONJ) and eNOS Polymorphisms in multiple myeloma patients: a single center experience
Tas Ozyurtseven, Betul; Serin, Istemi; Nursal, Ayse Feyda; Pehlivan, Sacide; Pehlivan, Mustafa (Bmc, 2021)Background Multiple myeloma (MM) constitutes approximately 10% of hematological malignancies. Bisphosphonates have established themselves in solid organ metastasis and multiple myeloma lytic bone lesions by inhibiting ... -
mi196a2 T/C variant as possible predisposal factor for ankylosing spondylitis in a Turkish population
Pehlivan, Sacide; Gursoy, Savas; Nursal, Ayse Feyda; Akaltun, Mazlum Serdar; Ozdilli, Kursat; Pehlivan, Mustafa (Elsevier Science Bv, 2018)[Abstract Not Available] -
The MIF rs755622 Variant may Increase Susceptibility of Breast Cancer but not Gastrointestinal Cancer in a Turkish Population
Pehlivan, Sacide; Işıksaçan, Nilgün; Pehlivan, Mustafa; Günaldı, Meral; Oyacı, Yasemin; Nursal, Ayşe Feyda (2020)OBJECTIVE An increasing number of epidemiological and molecular evidence proposes that inflammation is a significant factor in the etiology of cancers. Macrophage Migration Inhibitory Factor (MIF) encodes a lymphokine ... -
THE miR-196a2T/C VARIANT AS A POSSIBLE PREDISPOSING FACTOR FOR ANKYLOSING SPONDYLITIS IN A TURKISH POPULATION
Pehlivan, Sacide; Gürsoy, Savaş; Nursal, Ayşe Feyda; Akaltun, Mazlum Serdar; Özdilli, Kürşat; Pehlivan, Mustafa (2020)Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disorder. MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes. Altered miRNA expression has been implicated in the pathogenesis of ... -
The miRNA 196a2 rs11614913 variant has prognostic impact on Turkish patients with multiple myeloma
Kirik, Melya Pelin; Pehlivan, Mustafa; Nursal, Ayse Feyda; Oyaci, Yasemin; Pehlivan, Sacide; Serin, Istemi (Springernature, 2020)Objective Multiple myeloma (MM) arises from malignant plasma cells as a single clone in the bone marrow. Accumulating evidences have reported that there is an association between miR-196a2 (rs11614913) variant and various ... -
PER3 VNTR variant and susceptibility to smoking status/substance use disorder in a Turkish population
Nursal, Ayse Feyda; Aydin, Pinar Cetinay; Uysal, Mehmet Atilla; Pehlivan, Mustafa; Oyac, Yasemin; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Substance use and smoking exert devastating impact on sleep, especially hindering the ease of falling asleep, compromising the sleep maintenance, and distorting the sleep cycles. PERIOD genes are believed to ... -
Possible association between DNA repair gene variants and cannabis dependence in a Turkish cohort: a pilot study
Pehlivan, Sacide; Yazıcı, Ahmet Bülent; Aydın, Nazan; Nursal, Ayşe Feyda; Kurnaz, Selin; Öngel Atar, Ayça; Sever, Ülgen; Kıncır, Zeliha; Pehlivan, Mustafa; Çetinay Aydın, Pınar (Taylor and Francis Ltd., 2018)OBJECTIVE: Substance use disorder (SUD) has important effects on health and well-being. It is well known that genetic factors play a role in SUD. The purpose of this research was to investigate whether functional variants ... -
Role of MIF-173G/C and Mbl2 Codon 54A/B Variants in the Risk of Multiple Myeloma: An Association Study
Pehlivan, Mustafa; Nursal, Ayse Feyda; Gundes, Ilknur; Oyaci, Yasemin; Kivanc, Demet; Pehlivan, Sacide (Bentham Science Publ Ltd, 2021)Background: Multiple myeloma (MM) is a malignant disease manifested by the clonal proliferation of atypical plasma cells. Macrophage inhibitory factor (MIF) is one of the pleiotropic regulators in various biological and ... -
The roles of endothelial nitric oxide synthase (eNOS) and myeloperoxidase (MPO) genes in microtia
Büyükgüral, Berker; Pehlivan, Sacide; Nursal, Ayşe Feyda; Bekerecioğlu, Mehmet (Deomed Publishing, 2016)Objective:The aim of this study was to determine the relationshipbetween polymorphisms of endothelial nitric oxide synthase (eNOS)and myeloperoxidase (MPO) genes and development of microtia. Methods:Nineteen (11 males, 8 ... -
TNF-alpha-308 G/A variant may be associated with bipolar disorder in a Turkish population
Nursal, Ayse Feyda; Aytac, Hasan Mervan; Ciftci, Hayriye Senturk; Yazar, Menekse Sila; Oyaci, Yasemin; Pehlivan, Mustafa; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory multifunctional cytokine produced by macrophages. A dysregulation of the immune system contribute to the pathogenesis of bipolar disorder (BD). In ... -
What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?
Pehlivan, Sacide; Serin, Istemi; Nursal, Ayse Feyda; Oyaci, Yasemin; Gundes, Ilknur; Pehlivan, Mustafa (Springer, 2021)Background In today's practice, gene-based approaches come to the fore in the determination of prognosis and treatment preferences of multiple myeloma (MM). DNA methylation is one of the new approach parameters. DNA ... -
XRCC4 rs6869366 polymorphism is associated with susceptibility to both nicotine dependence and/or schizophrenia
Pehlivan, Sacide; Uysal, Metin Atilla; Aydın, Nazan; Nursal, Ayşe Feyda; Pehlivan, Mustafa; Yavuzlar, Hazal; Sever, Ülgen; Kurnaz, Selin; Yavuz, Fatih Kasım; Uysal, Suna; Çetinay Aydın, Pınar (Universidade de Sao Paulo, 2018)Background: Oxidative stress induced DNA damage has been assumed to contribute to the etiopathogenesis of schizophrenia (Sch). Smoking prevalence was more common in patients with Sch. The X-ray repair cross-complementation ...