Yazar "Akmeşe, Bediha" için listeleme
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Analytical application of polymethylene blue-multiwalled carbon nanotubes modified glassy carbon electrode on anticancer drug irinotecan and determination of its ionization constant value
Karadaş Bakırhan, Nurgül; Şanlı, Senem; Akmeşe, Bediha; Doğan Topal, Burcu; Can, Alp; Özkan, Sibel Ayşıl (Elsevier B.V., 2013)The voltammetric behavior of anticancer drug irinotecan (IRT) was investigated at poly (methylene blue)/multi-walled carbon nanotube (PMB/MWCNT) modified glassy carbon electrode (GCE). The modified electrode surface was ... -
Degradation studies and thermodynamic parameters in aqueous solution of chemotherapeutic agents: Daunorubicin, doxorubicin and vincristine
Bakırhan, Nurgül Karadaş; Akmeşe, Bediha; Göver, Tuğçe; Imanzadeh, Hamideh; Özkan, Sibel Ayşıl (2019)The degradation of daunorubicin (DNR), doxorubicin (DXR) and vincristine (VCR) as chemotherapeutic agents was investigated under stress conditions such as acidic and alkaline media, oxidation, photolytic and heating. The ... -
Determination of biogenic amines at low μg L–1levels as acetylacetone derivatives by RP-HPLC with UV-visible detection in expired apple juice samples
Akmeşe, Bediha; Asan, Abdurrahman (Slovensko Kemijsko Drustvo, 2018)An accurate and sensitive method for trace quantification of three biogenic amines in expired apple juice samples based on reversed-phase liquid chromatography (RP-HPLC) with UV-visible detection is described. Biogenic ... -
Determination of dissociation constants of some antifungal drugs by two different methods at 298 K
The dissociation constants of eight antifungal drugs (fenticonazole, isoconazole, itraconazole, ketoconazole, miconazole, ornidazole, tinidazole, tioconazole) have been determined in water and acetonitrile-water binary ... -
Determination of pKa values of some antipsychotic drugs by HPLC-correlations with the kamlet and taft solvatochromic parameters and HPLC analysis in dosage forms
Şanlı, Senem; Akmeşe, Bediha; Altun, Yüksel (2013)In this study, ionization constant (pKa) values were determined by using the dependence of the retention factor on the pH of the mobile phase for four ionizable drugs, namely, risperidone (RI), clozapine (CL), olanzapine ... -
Development of a flow-injection with spectrophotometric method for total iron in water samples
Asan, Adem; Akmeşe, Bediha (Hacettepe University, 2017)Asimple spectrophotometric flow-injection method is reported for the highly sensitive and fast determination of iron(III) and total iron. The method is based on the formation of iron(III)- (1-nitroso-2-naphthol-3,6 sulphonate) ... -
The development of forced degradation studies for the determination of daptomycin in urine at various conditions by using RP-LC method
Daptomycin is known as the first lipopeptide antibiotic shows activity against gram-positive bacteria. A fast, simple and repeatabile RP-LC method has been developed for the determination of daptomycin in mobile phase ... -
A novel RP-LC method for determination of pK a values of some anticancer agents and their assay
A simple, reliable, and rapid RP-LC method has been developed for the determination of some anticancer drugs (daunorubicin, doxorubicin and vincristine sulfate) in their dosage forms and human urine. These compounds are ... -
Optimization of the schiff-base reaction of acetylacetone with biogenic amines
Akmeşe, Bediha; Asan, Adem (Hitit University, 2017)In this work, optimum conditions for the derivatization reaction of biogenic amines (histamine, tyramine, putrecine, tryptamine, phenylethylamine, cadaverine, spermidine and spermine) with acetylacetone have been determined. ... -
A simple flow injection spectrophotometric procedure for direct determination of copper(II) in environmental samples
Akmeşe, Bediha; Aydın, Rukiye; Asan, Adem (Chemical Publishing Co., 2014)A new simple, rapid and sensitive flow-injection spectrophotometric detection method has been developed for the on-line determination of copper(II) in environmental water samples. The method is based on the measurement of ... -
Simultaneous determination of three phenolic compounds in water samples by pre-column derivatization coupled with reversed-phase high performance liquid chromatography
Asan, Adem; Konanç, M. Umut; Akmeşe, Bediha (Hacettepe University, 2018)In this study, a sensitive and accurate method for simultaneous separation and determination of three phenolic compounds (phenol, m-cresol and resorcinol) in water by revesed-phase high performance liquid chromatography ... -
A validated RP-HPLC method for the estimation of ornidazole in pharmaceutical dosage forms
Şanlı, Senem; Yıldırım, Tuğrul; Akmeşe, Bediha; Şanlı, Nurullah (Hacettepe University, 2012)A new, simple, rapid, selective, precise and accurate isocratic reverse phase high performance liquid chromatography assay has been developed and validated for assay of Ornidazole in tablet formulations. Tinidazole was ... -
A validated RP-LC method for salmeterol and fluticasone in their binary mixtures and their stress degradation behavior under ICH-recommended stress conditions
Akmeşe, Bediha; Şanlı, Senem; Şanlı, Nurullah; Asan, Abdurrahman (Maik Nauka Publishing / Springer SBM, 2014)Simple, accurate, precise and fully validated analytical methods for the simultaneous determination of salmeterol xinafoate and fluticasone propionate in combined dosage forms have been developed. These drugs were exposed ...
