Yazar "Alp, Ebru" için listeleme
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Analysis of MMP-7 and TIMP-2 gene polymorphisms in coronary artery disease and myocardial infarction: A Turkish case-control study
Alp, Ebru; Yılmaz, Akın; Tulmaç, Murat; Uğraş Dikmen, Asiye; Çengel, Atiye; Yalçın, Rıdvan; Menevşe, Emine Sevda (Elsevier (Singapore) Pte Ltd, 2017)Matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) have a significant role in tissue remodeling related to cardiac function. In earlier studies, MMP-7 A-181G (rs11568818), C-153T (rs11568819), ... -
Carboxylesterase 1, alpha 2a adrenergic receptor and noradrenalin transporter gene polymorphisms and their clinical effects in attention deficit hyperactivity disorder in Turkish children
Çetin, Fatih Hilmi; Işık, Yasemen; Alp, Ebru; Yılmaz, Akın; Taş Torun, Yasemen; Önen, İlke Hacer (ScienceDirect, 2018-06)The objective of this study was to examine the association between ADHD and G1287A polymorphism in the NET1 gene, C1291G polymorphism in the ADRA2A gene on the adrenergic pathway and Gly143Glu polymorphism in the CES1 gene ... -
Effects of EF-24, RAD001, and paclitaxel on the expression profiles of apoptotic and anti-apoptotic genes
Alp, Ebru; Yılmaz, Akın; Önen, İlke Hacer; Menevşe, Emine Sevda (Wolters Kluwer - Medknow, 2017)Context: Cancer cells exert differential responses to chemotherapeutics and inhibitors. To the best of our knowledge, a few or no research has been performed until now to determine the effect of EF-24 and RAD001 on MDA-MB-231 ... -
HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells
Yar Sağlam, Atiye Seda; Yılmaz, Akın; Önen, İlke Hacer; Alp, Ebru; Kayhan, Handan; Ekmekci, Abdullah (Leibniz Research Centre for Working Environment and Human Factors, 2016)Histone deacetylases (HDACs) play a major role in the regulation of chromatin structure and gene expression by changing acetylation status of histone and non-histone proteins. MS-275 (entinostat, MS) is a well-known ... -
HeLa hücrelerinde Sisplatinin MTOR, AKT, CCND1 ve STAT3 mRNA ifadesi üzerine etkileri
Alp, Ebru; Yılmaz, Akın; Önen, Hacer İlke; Konaç, Ece; Ekmekçi, Abdullah; Menevşe, Emine Sevda; Menevşe, Adnan (Gazi Üniversitesi, 2020)Giriş: Serviks kanseri, kadınlarda gözlenen malign tümörler arasında en yaygın görülen ve kadınlarda kanser sonucu gözlenen ölümler arasında ikinci sırada bulunan önemli bir hastalıktır. Platin temelli bir bileşik olan ... -
Reduced BCL2 and CCND1 mRNA expression in human cervical cancer HeLa cells treated with a combination of everolimus and paclitaxel
Yılmaz, Akın; Alp, Ebru; Önen, İlke Hacer; Menevşe, Emine Sevda (Termedia Publishing House Ltd., 2016)Aim of the study: Cervical cancer is the second most common malignancy in women worldwide. Everolimus displays direct effects on growth and proliferation of cancer cells via inhibition of mammalian target of rapamycin ...
