Yazar "Bağırıcı, Faruk" için listeleme
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Alpha-tocopherol decreases iron-induced hippocampal and nigral neuron loss
There are many studies about iron-induced neuronal hyperactivity and oxidative stress. Some reports also showed that iron levels rise in the brain in some neurodegenerative diseases such as Parkinson’s (PD) and Alzheimer’s ... -
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity: The role of L-type calcium channels in iron-induced neurotoxicity
Bostancı, Mehmet Ömer; Bağırıcı, Faruk (Informa Healthcare, 2013)Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ... -
Demirin neden olduğu purkinje hücre kaybı üzerine nitrik oksit sentaz inhibisyonunun koruyucu etkisi
Amaç: Demir, nöronal hiperaktivite ve oksidatif stresi indüklemek için sıklıkla kullanılan bir metaldir. Nitrik oksit sentaz (NOS) tarafından sentezlenen nitrik oksit ile hücre ölümü arasındaki ilişkiyi ortaya koyan bulgular ... -
Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy
Sefil, Fatih; Arık, Aliye E.; Acar, Meryem D.; Bostancı, Mehmet Ömer; Bağırıcı, Faruk; Kozan, Ramazan (E-Century Publishing Corporation, 2015)Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the ... -
Iron-induced cerebellar purkinje cell loss is ameliorated by flunarizine
Kozan, Ramazan; Bostancı, Mehmet Ömer; Nacar, Tuncer; Aslan, Ali; Bağırıcı, Faruk (Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TÜBİTAK), 2009)Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkinje cells in rats and the possible neuroprotective effect of flunarizine, a ... -
Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ... -
Sıçan serebellumunda demir nörotoksisitesine karşı vitamin E'nin koruyucu etkisi
Kozan, Ramazan; Bostancı, Mehmet Ömer; Ayas, Bülent; Aslan, Ali; Bağırıcı, Faruk (Fırat Üniversitesi, 2009)Amaç: Bu çalışmada, intraserebroventriküler olarak verilen demirin, sıçan serebellar Purkinje hücrelerinde oluşturduğu nörotoksisiteye karşı yağda çözülebilen güçlü bir antioksidan olan vitamin E'nin (?-tokoferol) etkisini ...
