Yazar "Gül, Melek" için listeleme
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Antioxidant and Cytotoxic Activity Studies of Sulfur Containing Glycine Imine Derivatives MCF-7 and DLD-1 Cell Lines
Mesci, Seda; Gül, Melek; Yıldırım, Tuba (Marmara Univ, Inst Health Sciences, 2021)Objective: To investigate the antioxidant and cytotoxic activities of sulfur-containing glycine imine derivatives MCF-7 (human breast adenocarcinoma) and DLD-1 (colorectal adenocarcinoma) cell lines. Methods: This study ... -
Downregulation of HSP27 by isoindole-derived pyrrolidines suppressing multidrug resistance (MDR) and inducing apoptosis in MCF-7 and DLD-1 cell lines
Mesci, Seda; Yazgan, Burak; Gül, Melek; Yıldırım, Tuba (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2024)In most cancer treatments, major problem arises from the prevention of cell death (apoptosis suppression) with the development of drug resistance. Anticancer agents that ensure elimination of drug resistance and drug-resistant ... -
Investigation of antioxidant activity and effect on cell viability of pyrrolidine compounds in MCF-7 (breast cancer) and DLD-1 (colon cancer) cell lines
Mesci, Seda; Gül, Melek; Yıldırım, Tuba (Al-Farabi Kazakh Natl Univ, 2021)In this study, it is aimed to investigate the effects of pyrrolidine compounds that are thought to be new drug candidates with effect on cell viability on cancer (MCF-7 and DLD-1) and normal (MCF-12A and CCD-18CO) cell ... -
A multidisciplinary approach to coronavirus disease (COVID-19)
Gediz Ertürk, Aliye; Şahin, Arzu; Batı Ay, Ebru; Pelit, Emel; Bağdatlı, Emine; Kulu, İrem; Gül, Melek; Mesci, Seda; Eryılmaz, Serpil; Oba İlter, Şirin; Yıldırım, Tuba (MDPI, 2021)Since December 2019, humanity has faced an important global threat. Many studies have been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus and the treatment of its disease. The priority ...