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Antiproliferative properties and structural analysis of newly synthesized Schiff bases bearing pyrazole derivatives and molecular docking studies
Sener, Nesrin; ozkinali, Sevil; Altunoglu, Yasemin Celik; Yerlikaya, Serife; Gokce, Halil; Zurnaci, Merve; Sener, Izzet (Elsevier, 2021)New pyrazole Schiffbases containing azo groups were synthesized using the condensation reaction between p-nitrobenzaldehyde and (E)-4-(phenyl)-1-H-pyrazole-3,5-diamine in the molar ratio of 1:2. Characterization of the ... -
Antiproliferative-antimicrobial properties and structural analysis of newly synthesized Schiff bases derived from some 1,3,4-thiadiazole compounds
Gur, Mahmut; Yerlikaya, Serife; Sener, Nesrin; Ozkinali, Sevil; Baloglu, Mehmet Cengiz; Gokce, Halil; Sener, Izzet (Elsevier, 2020)The 1,3,4-thiadiazole core has been mainly used as a pharmacological scaffold in medicinal chemistry. A series of Schiff bases derived from 5-substituted-1,3,4-thiadiazole-2-amine were designed and synthesized to investigate ...