Yazar "Kara, Aslı" için listeleme
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Astragalus membranaceus'dan yeşil sentez ile hazırlanan gümüş nanopartiküllerin antimikrobiyal ve antikanser etkinliğinin incelenmesi
Öztolüt, Ferhan (Hitit Üniversitesi, 2023)Gümüş, geçmişten günümüze sterilizasyon ya da yanık, ülser gibi hastalıkların tedavisi gibi pek çok farklı alanda kullanılmıştır. Gümüş nanopartiküller (AgNP) ise bakteri, virüs gibi mikroorganizmalar üzerinde kullanılan ... -
Development of novel self-assembled polymeric micelles from partially hydrolysed poly(2-ethyl-2-oxazoline)-co-PEI-b-PCL block copolymer as non-viral vectors for plasmid DNA in vitro transfection
Kara, Aslı; Öztürk, Naile; Esendağlı, Güneş; Özköse, Umut Uğur; Gülyüz, Sevgi; Yılmaz, Özgür; Telci, Dilek; Bozkır, Asuman; Vural, İmran (Taylor and Francis Ltd., 2018)A new efficient, non-viral gene delivery cationic polymeric micellar system was developed by partial hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOx) with two different hydrolysis percentages of PEtOx (30% and 60%) to reduce ... -
Evaluation of antitumor activity of a non-steroidal anti-inflammatory drug, ibuprofen, by a targeted nanoparticulate system
Öztürk, Naile; Kara, Aslı; Vural, İmran (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)In this study we aimed to develop a new targeted nanoparticulate system to obtain site specific delivery of ibuprofen and to determine its antitumor efficiency. The potential effect of ibuprofen as an antitumor agent was ... -
Formulation and In Vitro Evaluation of Telmisartan Nanoparticles Prepared by Emulsion-Solvent Evaporation Technique
Öztürk, Naile; Kara, Aslı; Vural, İmran (2020)bjectives: Telmisartan (TLM) is an antihypertensive drug that has been shown to have antiproliferative effects on cancer cells. It has low solubility and suboptimal oral bioavailability. To investigate the potential ... -
Genetic variation in natural populations of Capparis from Turkey, as revealed by RAPD analysis
Özbek, Özlem; Kara, Aslı (Springer-Verlag Wien, 2013)In this study, the genetic diversity of 15 Turkish natural Capparis populations was screened using the randomly amplified polymorphic DNA analysis (RAPD) technique. Ten RAPD primers produced 98 loci, 73 of which were ... -
In vitro CNS models
Kara, Aslı; Öztürk, Naile; Vural, İmran (Elsevier, 2017)Endothelial cells form a barrier between the blood and the central nervous system, namely the blood-brain barrier (BBB). Cellular components of the BBB, as well as tight junctions and paracellular barrier characterizations, ... -
Lysozyme-loaded lipid-polymer hybrid nanoparticles: preparation, characterization and colloidal stability evaluation
Devrim, Burcu; Kara, Aslı; Vural, İmran; Bozkır, Asuman (Taylor and Francis Ltd., 2016)Context: Lipid-polymer hybrid nanoparticles (LPNPs) are polymeric nanoparticles enveloped by lipid layers, which have emerged as a potent therapeutic nanocarrier alternative to liposomes and polymeric nanoparticles. ... -
A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles
Şekerdağ, Emine; Lüle, Sevda; Bozdağ Pehlivan, Sibel; Öztürk, Naile; Kara, Aslı; Kaffashi, Abbas; Vural, İmran; Işıkay, İlkay; Yavuz, Burçin; Karlı Oğuz, Hatice Kader; Söylemezoğlu, Figen; Gürsoy Özdemir, Yasemin; Mut, Melike (Elsevier B.V., 2017)New drug delivery systems are highly needed in research and clinical area to effectively treat gliomas by reaching a high antineoplastic drug concentration at the target site without damaging healthy tissues. Intranasal ... -
Türkiye'de yetişen Kapari (Capparis ssp.) bitkisinde genetik çeşitliliğin moleküler işaretleyicilerle karakterizasyonu
Kara, Aslı (Hitit Üniversitesi Fen Bilimleri Enstitüsü, 2012)Bu çalışmada Türkiye'de yetişen 15 Capparis L. popülasyonunda genetik çeşitlilik rastgele çoğaltılmış polimorfik DNA analizi (RAPD) tekniği kullanılarak araştırıldı. Çalışmada kullanılan 10 RAPD primeri %100'ü polimorfik ...
