Yazar "Nursal, Ayse Feyda" için listeleme
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CNR2 rs2229579 and COMT Val158Met variants, but not CNR2 rs2501432, IL-17 rs763780 and UCP2 rs659366, contribute to susceptibility to substance use disorder in the Turkish population
Kurnaz, Selin; Yazici, Ahmet Bulent; Nursal, Ayse Feyda; Aydin, Pinar Cetinay; Atar, Ayca Ongel; Aydin, Nazan; Pehlivan, Sacide (Taylor & Francis Ltd, 2019)OBJECTIVE: Substance use disorders (SUD) are among the most important public health problems throughout the world. We investigated whether COMT (Val108/158Met), CNR2 (rs2501432 and rs2229579), UCP2 (rs659366), and IL-17 ... -
Do UCP2, IL-17, mi196a2, and NR3C1 gene variants contribute to the risk of microtia? A preliminary study in Turkish population
Ozdilli, Kursat; Bekerecioglu, Mehmet; Nursal, Ayse Feyda; Pehlivan, Mustafa; Sever, Ulgen; Buyukgural, Berker; Pehlivan, Sacide (Elsevier Science Bv, 2018)[Abstract Not Available] -
eNOS and VEGF Variants Might Increase the Risk of Pancreatic Cancer
Hasan Dagmura; Yigit, Serbulent; Gumusay, Ozge; Nursal, Ayse Feyda; Daldal, Emin; Karakus, Nevin (Pleiades Publishing Inc, 2021)Background: Endothelial nitric oxide synthase (eNOS) is essential in chronic inflammation and carcinogenesis. The association between variants in vascular endothelial growth factor (VEGF) and several cancers still remains ... -
Global and glucocorticoid receptor gene-specific (NR3C1) DNA methylation analysis in patients with cannabinoid or synthetic cannabinoid use disorder
Pehlivan, Sacide; Aytac, Hasan Mervan; Aydin, Pinar Cetinay; Nursal, Ayse Feyda; Pehlivan, Mustafa (Elsevier Ireland Ltd, 2021)This study investigates the relationship between cannabinoid use disorder (CUD) or synthetic cannabinoid use disorder (SCUD) and the global methylation, methylation of NR3C1 gene promotor, and NR3C1 BclI poly-morphism, ... -
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus
Yigit, Serbulent; Nursal, Ayse Feyda; Uzun, Suheyla; Rustemoglu, Husniye; Dashatan, Payam Amiri; Soylu, Huseyin; Karakus, Nevin (Bentham Science Publ Ltd, 2021)Purpose: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN. Methods: A total of 598 subjects were enrolled in the study. ... -
The Impact of PER3 VNTR Polymorphism on the Development of Schizophrenia in a Turkish Population
Ozsoy, Filiz; Yigit, Serbulent; Nursal, Ayse Feyda; Kulu, Muberra; Karakus, Nevin (Pleiades Publishing Inc, 2021)Introduction: Up to 80% of patients who suffer from schizophrenia have sleep impairments, which affect physical and mental health, as well as quality of life. Several tandem repeat polymorphisms (VNTRs) in the Period 3 ... -
Importance of NPC1 Gene 644 A -> G Mutation in Coronary Artery Disease
Ozturk, Sibel Demir; Celik, Atac; Nursal, Ayse Feyda; Tekcan, Akin; Rustemoglu, Aydin; Karakus, Nevin; Yigit, Serbulent (Kamla-Raj Enterprises, 2017)Coronary artery disease (CAD) is the most prominent cause of mortality worldwide. The basis of CAD pathogenesis is the occlusion of coroner vessels progressively due to atherosclerotic plaques. NPCI gene plays a critical ... -
Investigating the eNOS and IFN-gamma Gene Variants Susceptible to Bipolar Disorder or Schizophrenia in a Turkish Cohort
Pehlivan, Sacide; Aytac, Hasan Mervan; Ciftci, Hayriye Senturk; Oyaci, Yasemin; Pehlivan, Mustafa; Nursal, Ayse Feyda (Turkish Assoc Psychopharmacology, 2020)Background: Schizophrenia (Sch) and bipolar disorder (BD) are debilitating chronic psychiatric disorders that are both etiologically and clinically heterogeneous. According to the gathered evidence, multiple mental disorders ... -
Is there any Association between the Functional Variants of the NOS3 Gene and Psoriasis?
Pehlivan, Sacide; Inaloz, Huseyin Serhat; Nursal, Ayse Feyda; Gulel, Aslihan; Pehlivan, Mustafa (Aves, 2018)Introduction: Psoriasis (Ps) is a chronic, immune-mediated inflammatory skin disorder with an incompletely understood etiology. The aim of this study was to investigate the relationship between the suspectibility to Ps and ... -
Medication-related osteonecrosis of the jaw (MRONJ) and eNOS Polymorphisms in multiple myeloma patients: a single center experience
Tas Ozyurtseven, Betul; Serin, Istemi; Nursal, Ayse Feyda; Pehlivan, Sacide; Pehlivan, Mustafa (Bmc, 2021)Background Multiple myeloma (MM) constitutes approximately 10% of hematological malignancies. Bisphosphonates have established themselves in solid organ metastasis and multiple myeloma lytic bone lesions by inhibiting ... -
mi196a2 T/C variant as possible predisposal factor for ankylosing spondylitis in a Turkish population
Pehlivan, Sacide; Gursoy, Savas; Nursal, Ayse Feyda; Akaltun, Mazlum Serdar; Ozdilli, Kursat; Pehlivan, Mustafa (Elsevier Science Bv, 2018)[Abstract Not Available] -
The miRNA 196a2 rs11614913 variant has prognostic impact on Turkish patients with multiple myeloma
Kirik, Melya Pelin; Pehlivan, Mustafa; Nursal, Ayse Feyda; Oyaci, Yasemin; Pehlivan, Sacide; Serin, Istemi (Springernature, 2020)Objective Multiple myeloma (MM) arises from malignant plasma cells as a single clone in the bone marrow. Accumulating evidences have reported that there is an association between miR-196a2 (rs11614913) variant and various ... -
MTHFR gene C677T and A1298C variants are associated with FMF risk in a Turkish cohort
Nursal, Ayse Feyda; Kaya, Suheyla; Sezer, Ozlem; Karakus, Nevin; Yigit, Serbulent (Wiley, 2018)BackgroundMethylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in homocysteine (Hcy) metabolism. We aimed to evaluate a possible relationship between MTHFR gene C677T (rs 1801133), A1298C (rs 1801131) variants ... -
PER3 VNTR variant and susceptibility to smoking status/substance use disorder in a Turkish population
Nursal, Ayse Feyda; Aydin, Pinar Cetinay; Uysal, Mehmet Atilla; Pehlivan, Mustafa; Oyac, Yasemin; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Substance use and smoking exert devastating impact on sleep, especially hindering the ease of falling asleep, compromising the sleep maintenance, and distorting the sleep cycles. PERIOD genes are believed to ... -
Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer
Dagmura, Hasan; Yigit, Serbulent; Nursal, Ayse Feyda; Duman, Esra; Gumusay, Ozge (Mary Ann Liebert, Inc, 2021)Objective: Pancreatic cancer (PC) is a serious disease with poor outcomes, and its prevalence has been increasing steadily. The circadian rhythm (CR) is involved in multiple physiological events and maintains homeostasis. ... -
Role of MIF-173G/C and Mbl2 Codon 54A/B Variants in the Risk of Multiple Myeloma: An Association Study
Pehlivan, Mustafa; Nursal, Ayse Feyda; Gundes, Ilknur; Oyaci, Yasemin; Kivanc, Demet; Pehlivan, Sacide (Bentham Science Publ Ltd, 2021)Background: Multiple myeloma (MM) is a malignant disease manifested by the clonal proliferation of atypical plasma cells. Macrophage inhibitory factor (MIF) is one of the pleiotropic regulators in various biological and ... -
TNF-alpha-308 G/A variant may be associated with bipolar disorder in a Turkish population
Nursal, Ayse Feyda; Aytac, Hasan Mervan; Ciftci, Hayriye Senturk; Yazar, Menekse Sila; Oyaci, Yasemin; Pehlivan, Mustafa; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory multifunctional cytokine produced by macrophages. A dysregulation of the immune system contribute to the pathogenesis of bipolar disorder (BD). In ... -
What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?
Pehlivan, Sacide; Serin, Istemi; Nursal, Ayse Feyda; Oyaci, Yasemin; Gundes, Ilknur; Pehlivan, Mustafa (Springer, 2021)Background In today's practice, gene-based approaches come to the fore in the determination of prognosis and treatment preferences of multiple myeloma (MM). DNA methylation is one of the new approach parameters. DNA ...
