Yazar "Tekcan, Akın" için listeleme
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Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
Nursal, Ayşe Feyda; Türkmen, Ercan; Uzun Kaya, Süheyla; Tekcan, Akın; Sezer, Özlem; Çelik, Sümeyya Deniz; Yiğit, Serbülent (Iranian Society of Nephrology, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
Association of XRCC1 and XPD functional gene variants with nicotine dependence and/or schizophrenia: a case-control study and in silico analysis
Pehlivan, Sacide; Aydın, Nizamettin; Nursal, Ayşe Feyda; Uysal, Mehmet Atilla; Pehlivan, Mustafa; Tekcan, Akın; Yavuz, Fatih Kasım; Sever, Ülgen; Yavuzlar, Hazal; Kurnaz, Selin; Uysal, Seda; Çetinay Aydın, Pınar (Taylor and Francis Ltd., 2019)OBJECTIVE: The role of DNA repair mechanisms has received attention recently in schizophrenia (Sch). Sch patients show an increased prevalence of nicotine dependence (ND). This study aimed to find out whether functional ... -
C Deletion in Exon 4 Codon 63 of p53 Gene in Turkish Patients with Oral Squamous Cell Carcinoma
Tekcan, Akın; Gümüşay, Özge; Nursal, Ayşe Feyda; Yiğit, Serbülent; Yıldız, Serkan; Tümer, Mehmet Kemal (2020)OBJECTIVE Oral squamous cell carcinoma (OSCC) is the most frequently seen oral malignancy and accounts for up to 80-90% of all malignant neoplasms that occurin the oral cavity. The p53 tumor suppressor gene plays a crucial ... -
Effect of a functional variant of tumor necrosis factor-β gene in temporomandibular disorders: a pilot study
Yerliyurt, Kaan; Nursal, Ayşe Feyda; Tekcan, Akın; Karakuş, Nevin; Tümer, Mehmet Kemal; Yiğit, Serbülent (John Wiley and Sons Inc., 2019)Background: Temporomandibular disorders (TMD) are a group of conditions that cause chronic orofacial pain. The tumor necrosis factor ? (TNF-?) is a proinflammatory cytokine that is involved in the various aspects of the ... -
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
Tümer, Mehmet Kemal; Nursal, Ayşe Feyda; Tekcan, Akın; Yerliyurt, Kaan; Geyko, Anastasia; Yiğit, Serbülent (John Wiley and Sons Inc., 2018)Background: Temporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ... -
Impact of glucocorticoid receptor gene Bcl-1 variant on temporomandibular disorders
Tümer, Mehmet Kemal; Yerliyurt, Kaan; Nursal, Ayşe Feyda; Karakuş, Nevin; Tekcan, Akın; Yiğit, Serbülent (Scientific Publishers of India, 2017)Objectives: Temporomandibular Disorders (TMD) constitute a heterogeneous group of disorders characterized by alterations in mandibular movement. The aim of this study was to investigate the association between the Bcl1 ... -
Impact of the Functional VNTR Variants of the Interleukin-1 Receptor Antagonist and Interleukin-4 Genes on Oral Squamous Cell Carcinoma
Introduction: It has been shown that the host immune response and chronic inflammation could play a role as important risk factors for cancer. Oral squamous cell carcinoma (OSCC) is a common cancer worldwide. In this study, ... -
Macrophage migration inhibitory factor -173GC variant might increase the risk of behçet's disease
Nursal, Ayşe Feyda; Yiğit, Serbülent; Tural, Ercan; Kalkan, Göknur; Tümer, Mehmet Kemal; Tekcan, Akın (S. Karger AG, 2018)Objective: The aim of the present study was to investigate any possible association between the macrophage migration inhibitory factor (MIF) -173GC variant and Behçet's disease (BD) in a group of Turkish patients. Subjects ...
