Yazar "Yiğit, Serbülent" için listeleme
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ACAN Gene VNTR Polymorphism and Intervertebral Disc Degeneration in a Turkish Population
Öz, Tuba; Kaya, İsmail; Nursal, Ayşe Feyda; Aydın, Hasan Emre; Demir, Osman; Yiğit, Serbülent (2020)Aim: Intervertebral disc degeneration (IVDD) is caused by several genetic and environmental factors. Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. The aim of ... -
Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
Nursal, Ayşe Feyda; Türkmen, Ercan; Uzun Kaya, Süheyla; Tekcan, Akın; Sezer, Özlem; Çelik, Sümeyya Deniz; Yiğit, Serbülent (Iranian Society of Nephrology, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
C Deletion in Exon 4 Codon 63 of p53 Gene in Turkish Patients with Oral Squamous Cell Carcinoma
Tekcan, Akın; Gümüşay, Özge; Nursal, Ayşe Feyda; Yiğit, Serbülent; Yıldız, Serkan; Tümer, Mehmet Kemal (2020)OBJECTIVE Oral squamous cell carcinoma (OSCC) is the most frequently seen oral malignancy and accounts for up to 80-90% of all malignant neoplasms that occurin the oral cavity. The p53 tumor suppressor gene plays a crucial ... -
Effect of a functional variant of tumor necrosis factor-β gene in temporomandibular disorders: a pilot study
Yerliyurt, Kaan; Nursal, Ayşe Feyda; Tekcan, Akın; Karakuş, Nevin; Tümer, Mehmet Kemal; Yiğit, Serbülent (John Wiley and Sons Inc., 2019)Background: Temporomandibular disorders (TMD) are a group of conditions that cause chronic orofacial pain. The tumor necrosis factor ? (TNF-?) is a proinflammatory cytokine that is involved in the various aspects of the ... -
Genetic Variations of miRNAs and the Risk of Oral Squamous Cell Carcinoma: A Case-control Study
Aim: In this study, we investigated the association between two miRNA variants and the risk of oral squamous cell carcinoma (OSCC), and explored the interaction between clinical factors in the Turkish population. Methods: ... -
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
Tümer, Mehmet Kemal; Nursal, Ayşe Feyda; Tekcan, Akın; Yerliyurt, Kaan; Geyko, Anastasia; Yiğit, Serbülent (John Wiley and Sons Inc., 2018)Background: Temporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ... -
Il-1β and IL-1Ra variant profiles in Turkish patients with diabetic peripheral neuropathy
Nursal, Ayşe Feyda; İnanır, Ahmet; Rüstemoğlu, Aydın; Uzun, Süheyla; Şahin, Kübra; Yiğit, Serbülent (Bentham Science Publishers B.V., 2019)Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of Type 2 diabetes mellitus (T2DM). This study was conducted to investigate the possible association between interleukin-1β (IL-1β) ... -
Impact of glucocorticoid receptor gene Bcl-1 variant on temporomandibular disorders
Tümer, Mehmet Kemal; Yerliyurt, Kaan; Nursal, Ayşe Feyda; Karakuş, Nevin; Tekcan, Akın; Yiğit, Serbülent (Scientific Publishers of India, 2017)Objectives: Temporomandibular Disorders (TMD) constitute a heterogeneous group of disorders characterized by alterations in mandibular movement. The aim of this study was to investigate the association between the Bcl1 ... -
Impact of the Functional VNTR Variants of the Interleukin-1 Receptor Antagonist and Interleukin-4 Genes on Oral Squamous Cell Carcinoma
Introduction: It has been shown that the host immune response and chronic inflammation could play a role as important risk factors for cancer. Oral squamous cell carcinoma (OSCC) is a common cancer worldwide. In this study, ... -
Investigation of the role of interleukin-1 receptor antagonist VNTR variant on the Behçet’s disease
Dursun, Gul; Nursal, Ayşe Feyda; Demir, Helin Deniz; Karakuş, Nevin; Demir, Osman; Yiğit, Serbülent (2018)Objective: Behçet’s disease (BD), a chronic multisystem inflammatory disorder, is mainly characterized by relapsing periods of a wide range of clinical symptoms. Several cytokine genes may play important roles in the ... -
Macrophage migration inhibitory factor -173GC variant might increase the risk of behçet's disease
Nursal, Ayşe Feyda; Yiğit, Serbülent; Tural, Ercan; Kalkan, Göknur; Tümer, Mehmet Kemal; Tekcan, Akın (S. Karger AG, 2018)Objective: The aim of the present study was to investigate any possible association between the macrophage migration inhibitory factor (MIF) -173GC variant and Behçet's disease (BD) in a group of Turkish patients. Subjects ... -
The Role of Interleukin-4 VNTR Polymorphism in Dysmenorrhea Development
Aim: Primary dysmenorrhea (PD) is among the most common gynecological diseases in young women presenting to emergency department. It has been shown that cytokines played roles in PD pathogenesis. Interleukin-4 (IL-4), a ... -
Significance of IL-1Ra and IL-6 gene variants in Turkish patients with Crimean-Congo hemorrhagic fever
Say Coşkun, Umut Safiye; Nursal, Ayşe Feyda; Güneş, Ferda; Rüstemoğlu, Aydın; Yaylı, Abdullah; Karakuş, Nevin; Barut, Hüseyin Şener; Yiğit, Serbülent (Wolters Kluwer Medknow Publications, 2019)Objective: To investigate the association between IL-1Ra variable number of tandem repeat (rs2234663), IL-6 -597GA (rs1800797), IL-6 -572GC (rs1800796) and the risk of Crimean-Congo hemorrhagic fever (CCHF) in the Turkish ...
