Yazar "Yigit, Serbulent" için listeleme
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Analysis of Interleukin-1 Receptor Antagonist Variable Number Tandem Repeat Variant in Recurrent Aphthous Stomatitis
Tekcan, Akin; Yigit, Serbulent; Nursal, Ayse F.; Tumer, Mehmet K.; Yerliyurt, Kaan; Kuruca, Nilufer (Bentham Science Publ Ltd, 2021)Background/Aims: Recurrent aphthous stomatitis (RAS) is one of the common oral inflammatory diseases. As immunological and genetic factors have been held responsible for the pathogenesis of RAS, the objective of this study ... -
eNOS and VEGF Variants Might Increase the Risk of Pancreatic Cancer
Hasan Dagmura; Yigit, Serbulent; Gumusay, Ozge; Nursal, Ayse Feyda; Daldal, Emin; Karakus, Nevin (Pleiades Publishing Inc, 2021)Background: Endothelial nitric oxide synthase (eNOS) is essential in chronic inflammation and carcinogenesis. The association between variants in vascular endothelial growth factor (VEGF) and several cancers still remains ... -
Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features
Ozsoy, Filiz; Nursal, Ayse F.; Karakus, Nevin; Demir, Meral O.; Yigit, Serbulent (Bentham Science Publ Ltd, 2021)Objective: Major Depressive Disorder (MDD) is a major health problem worldwide. Estrogen interacts with the central nervous system and has been shown to affect anxiety and depressive behavior. Estrogen mediates its effects ... -
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus
Yigit, Serbulent; Nursal, Ayse Feyda; Uzun, Suheyla; Rustemoglu, Husniye; Dashatan, Payam Amiri; Soylu, Huseyin; Karakus, Nevin (Bentham Science Publ Ltd, 2021)Purpose: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN. Methods: A total of 598 subjects were enrolled in the study. ... -
The Impact of PER3 VNTR Polymorphism on the Development of Schizophrenia in a Turkish Population
Ozsoy, Filiz; Yigit, Serbulent; Nursal, Ayse Feyda; Kulu, Muberra; Karakus, Nevin (Pleiades Publishing Inc, 2021)Introduction: Up to 80% of patients who suffer from schizophrenia have sleep impairments, which affect physical and mental health, as well as quality of life. Several tandem repeat polymorphisms (VNTRs) in the Period 3 ... -
Importance of NPC1 Gene 644 A -> G Mutation in Coronary Artery Disease
Ozturk, Sibel Demir; Celik, Atac; Nursal, Ayse Feyda; Tekcan, Akin; Rustemoglu, Aydin; Karakus, Nevin; Yigit, Serbulent (Kamla-Raj Enterprises, 2017)Coronary artery disease (CAD) is the most prominent cause of mortality worldwide. The basis of CAD pathogenesis is the occlusion of coroner vessels progressively due to atherosclerotic plaques. NPCI gene plays a critical ... -
Influence of ESR1 Variants on Clinical Characteristics and Fibromyalgia Syndrome in Turkish Women
Arslan, Habibe S.; Nursal, Ayse F.; Inanir, Ahmet; Karakus, Nevin; Yigit, Serbulent (Bentham Science Publ Ltd, 2021)Background: Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain. It is more common in women than in men, and sex hormones may play a role in this predominance. Therefore, this research investigated ... -
MTHFR gene C677T and A1298C variants are associated with FMF risk in a Turkish cohort
Nursal, Ayse Feyda; Kaya, Suheyla; Sezer, Ozlem; Karakus, Nevin; Yigit, Serbulent (Wiley, 2018)BackgroundMethylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in homocysteine (Hcy) metabolism. We aimed to evaluate a possible relationship between MTHFR gene C677T (rs 1801133), A1298C (rs 1801131) variants ... -
Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer
Dagmura, Hasan; Yigit, Serbulent; Nursal, Ayse Feyda; Duman, Esra; Gumusay, Ozge (Mary Ann Liebert, Inc, 2021)Objective: Pancreatic cancer (PC) is a serious disease with poor outcomes, and its prevalence has been increasing steadily. The circadian rhythm (CR) is involved in multiple physiological events and maintains homeostasis. ...
