ORCID "Yigit, Serbulent / 0000-0002-1019-3964" için listeleme
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Analysis of Interleukin-1 Receptor Antagonist Variable Number Tandem Repeat Variant in Recurrent Aphthous Stomatitis
Tekcan, Akin; Yigit, Serbulent; Nursal, Ayse F.; Tumer, Mehmet K.; Yerliyurt, Kaan; Kuruca, Nilufer (Bentham Science Publ Ltd, 2021)Background/Aims: Recurrent aphthous stomatitis (RAS) is one of the common oral inflammatory diseases. As immunological and genetic factors have been held responsible for the pathogenesis of RAS, the objective of this study ... -
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus
Yigit, Serbulent; Nursal, Ayse Feyda; Uzun, Suheyla; Rustemoglu, Husniye; Dashatan, Payam Amiri; Soylu, Huseyin; Karakus, Nevin (Bentham Science Publ Ltd, 2021)Purpose: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN. Methods: A total of 598 subjects were enrolled in the study. ... -
Importance of NPC1 Gene 644 A -> G Mutation in Coronary Artery Disease
Ozturk, Sibel Demir; Celik, Atac; Nursal, Ayse Feyda; Tekcan, Akin; Rustemoglu, Aydin; Karakus, Nevin; Yigit, Serbulent (Kamla-Raj Enterprises, 2017)Coronary artery disease (CAD) is the most prominent cause of mortality worldwide. The basis of CAD pathogenesis is the occlusion of coroner vessels progressively due to atherosclerotic plaques. NPCI gene plays a critical ... -
MTHFR gene C677T and A1298C variants are associated with FMF risk in a Turkish cohort
Nursal, Ayse Feyda; Kaya, Suheyla; Sezer, Ozlem; Karakus, Nevin; Yigit, Serbulent (Wiley, 2018)BackgroundMethylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in homocysteine (Hcy) metabolism. We aimed to evaluate a possible relationship between MTHFR gene C677T (rs 1801133), A1298C (rs 1801131) variants ...