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Toplam kayıt 24, listelenen: 1-10
Il-1β and IL-1Ra variant profiles in Turkish patients with diabetic peripheral neuropathy
(Bentham Science Publishers B.V., 2019)
Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of Type 2 diabetes mellitus (T2DM). This study was conducted to investigate the possible association between interleukin-1β (IL-1β) ...
Techniques for nucleic acid engineering: The foundation of gene manipulation
(Elsevier Inc., 2017)
The journey of nucleic acid isolation and characterization has been a long one starting in the late 1800s. DNA isolation has led the way due to its stable chemical characteristic. Since its initial implementation the demand ...
Impact of glucocorticoid receptor gene Bcl-1 variant on temporomandibular disorders
(Scientific Publishers of India, 2017)
Objectives: Temporomandibular Disorders (TMD) constitute a heterogeneous group of disorders characterized by alterations in mandibular movement. The aim of this study was to investigate the association between the Bcl1 ...
Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
(Iranian Society of Nephrology, 2018)
Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ...
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
(John Wiley and Sons Inc., 2018)
Background: Temporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ...
The possible role of CCR5Δ32 mutation in Crimean-Congo hemorrhagic fever infection
(John Wiley and Sons Inc., 2017)
Crimean-Congo hemorrhagic fever infection (CCHF) is a viral zoonosis. The pathogenesis of this disease has not been established so far, however, cytokines account for its progression and outcome. The aim of the present ...
C Deletion in Exon 4 Codon 63 of p53 Gene in Turkish Patients with Oral Squamous Cell Carcinoma
(2020)
OBJECTIVE Oral squamous cell carcinoma (OSCC) is the most frequently seen oral malignancy and accounts for up to 80-90% of all malignant neoplasms that occurin the oral cavity. The p53 tumor suppressor gene plays a crucial ...
Correlation of HER2/TOP2A Gene Aberrations with RASSF1A/APC Gene Methylation Status in High-Risk Breast Cancer
(2020)
OBJECTIVE Breast cancer (BC) is a heterogeneous malignancy and differs widely among different patients. The aim of this study was to investigate the relationship between the HER2/TOP2A gene aberrations and promoter methylation ...
Endotelyal nitrik oksit sentaz (eNOS) ve miyeloperoksidaz (MPO) genlerin mikrotiyadaki rolü
(2016)
Amaç: Bu çalışmanın amacı endotelyal nitrik oksit sentaz (eNOS) polimorfizmleriyle miyeloperoksidaz (MPO) genleri ve mikrotiya gelişimi arasındaki ilişkiyi belirlemekti. Yöntem:Çalışmaya akraba olmayan 19 (11 erkek, 8 ...
Association of Myeloperoxidase Gene Functional Variant with Schizophrenia and Smoking in a Turkish Population
(2020)
Objective: Etiopathogenesis of schizophrenia (SCZ) involves several risk genes that induce inflammation, environmental stress factors and changes in the innate immune system. Patients with SCZ have the highest rate of ...