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Comparison of Different Anticoagulation Regimens Regarding Maternal and Fetal Outcomes in Pregnant Patients With Mechanical Prosthetic Heart Valves (from the Multicenter ANATOLIA-PREG Registry)
(Excerpta Medica Inc-Elsevier Science Inc, 2020)
Mechanical prosthetic heart valves (MPHVs) are highly thrombogenic, and a pregnancyinduced procoagulant status increases the risk of MPHV thrombosis. Despite numerous case reports, 2 major registries and meta-analyses/systematic ...
Diagnosis, treatment & management of prosthetic valve thrombosis: the key considerations
(Taylor & Francis Ltd, 2020)
Introduction: Prosthetic heart valve thrombosis is a life-threatening complication after valve replacement surgery. Although subtherapeutic anticoagulation is the main cause, there are many other conventional and esoteric ...
Low Dose and Slow/Ultra-Slow Infusion Thrombolytic Therapy Regimens are Effective and Safe in Patients With Prosthetic Valve Thrombosis
(Elsevier Science Inc, 2020)
To the Editor,We have recently read with great interest the article by Milneet al. entitled‘Management and outcomes of prosthetic valvethrombosis. An Australian case series from the NorthernTerritory’[1].
Clinical safety and efficacy of thrombolytic therapy with low-dose prolonged infusion of tissue type plasminogen activator in patients with intermediate-high risk pulmonary embolism
(Lippincott Williams & Wilkins, 2020)
The patients with intermediate-high risk pulmonary embolism who have acute right ventricular (RV) dysfunction and myocardial injury without overt hemodynamic compromise may be candidates for thrombolytic therapy. Alternative ...
The value of brain natriuretic peptide in the prosthetic valve thrombosis
(Lippincott Williams & Wilkins, 2020)
We aimed to investigate how prosthetic valve thrombosis (PVT) affects brain natriuretic peptide (BNP) levels and how BNP changes following thrombolytic therapy. The study included 70 consecutive patients with left-sided ...
A comprehensive review of the diagnosis and management of mitral paravalvular leakage
(Turkish Soc Cardiology, 2020)
Mitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, ...
Improvement of endothelial function early after thrombolytic therapy in patients with prosthetic heart valve thrombosis
(2020)
Objective: Prosthetic valve thrombosis (PVT) is a serious complication among patients with prosthetic heart valves. Thrombolytic therapy (TT) is now widely used as first-line treatment for PVT. Endothelial dysfunction has ...