Fast method for synthesis of alkyl and aryl-N-methylnitrones
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CitationYavuz, S., Özkan, H., Çolak, N., Yıldırır, Y. (2011). Fast method for synthesis of alkyl and aryl-N-methylnitrones. Molecules, 16(8), 6677-6683.
A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N-methylhydroxylamine hydrochloride and Na2CO3-Na2SO4 by simply grinding at room temperature without using solvent.