Gelişmiş Arama

Basit öğe kaydını göster

dc.contributor.authorÇelik, Oğuzhan
dc.contributor.authorDemirci, Erkan
dc.contributor.authorAydın, Mustafa
dc.contributor.authorKarabağ, Turgut
dc.contributor.authorKalçık, Macit
dc.date.accessioned2019-05-13T09:07:29Z
dc.date.available2019-05-13T09:07:29Z
dc.date.issued2017
dc.identifier.citationÇelik, O., Demirci, E., Aydın, M., Karabağ, T., Kalçık, M. (2017). Evaluation of ghrelin levels and endothelial functions in patients with coronary slow flow phenomenon. Interventional Medicine and Applied Science, 9(3), 154-159.en_US
dc.identifier.issn2061-1617
dc.identifier.urihttps://doi.org/10.1556/1646.9.2017.27
dc.identifier.urihttps://hdl.handle.net/11491/1812
dc.description.abstractBackground: Ghrelin has recently been reported to have beneficial effects on cardiac contractile functions and coronary blood flow. The main purpose of this study was to investigate the role of ghrelin in the pathogenesis of coronary slow flow (CSF) together with endothelial functions. Methods: Twenty-five patients having normal coronary arteries with CSF and 25 controls with normal coronary flow were included into the study. The quantitative measurement of coronary blood flow was performed for each coronary artery using the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method. Ghrelin levels were measured using the enzyme-linked immunosorbent assay method from venous blood samples. Endothelial functions were evaluated from the brachial artery with the flow-mediated dilation (FMD) and nitrate-related dilation methods. Results: There was a significant difference in terms of mean TFC values between the control and CSF groups (p < 0.001 for all coronary arteries). The mean FMD percentage among patients with CSF was lower than that of the control group (5.9 ± 0.8 vs. 10.7% ± 1.1%; p < 0.001). A moderate negative correlation was observed between the FMD percentages and the TFCs. There was no relationship between the TFC and ghrelin levels. Conclusion: Plasma ghrelin levels seem to be uninfluential while impaired endothelial functions play an important role in the etiopathogenesis of CSF. © 2017 The Author(s).en_US
dc.language.isoeng
dc.publisherAkademiai Kiado Rt.en_US
dc.relation.isversionof10.1556/1646.9.2017.27en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectCoronary Arteryen_US
dc.subjectCoronary Slow Flowen_US
dc.subjectEndothelial Dysfunctionen_US
dc.subjectGhrelinen_US
dc.subjectTimi Frame Counen_US
dc.titleEvaluation of ghrelin levels and endothelial functions in patients with coronary slow flow phenomenonen_US
dc.typearticleen_US
dc.relation.journalInterventional Medicine and Applied Scienceen_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.identifier.volume9en_US
dc.identifier.issue3en_US
dc.identifier.startpage154en_US
dc.identifier.endpage159en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster

info:eu-repo/semantics/openAccess
Aksi belirtilmediği sürece bu öğenin lisansı: info:eu-repo/semantics/openAccess