Atom-economical synthesis of complex heterocycles with N-O moiety

Abstract

A concise and facile method for the synthesis of heterocyclic compounds with N-O tether was introduced. The two important steps of the synthesis are a Mitsunobu reaction and C-H activation. The Mitsunobu protocol allows to form the N-O moiety in the molecule, while subsequent C-H activation leads to heterocycles. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.