Yazar "Özkan, Sibel Ayşıl" için Makale Koleksiyonu listeleme
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Optimization of stability indicating LC method for the sensitive in vitro determination from solid lipid nanoparticles and ex vivo analysis from rat skin of etofenamate
Gümüştaş, Mehmet; Şengel Türk, Ceyda Tuba; Badıllı, Ulya; Amasya, Gülin; Özkan, Sibel Ayşıl; Tarımcı, Nilüfer (Bentham Science Publishers B.V., 2017)Introduction: Etofenamate (2-(2-hydroxyethoxy) ethyl 2-[[3-(trifluoromethyl)phenyl]amino] benzoate) (ETO) is a yellowish viscous liquid which is a nonsteroidal anti-inflammatory drug (NSAID) that has been applied topically ... -
Polarographic investigation of dienogest
Baymak Çelik, Melek Şirin; Çelik, Hayati; Karadaş Bakırhan, Nurgül; Uslu, Bengi; Özkan, Sibel Ayşıl (Electrochemical Society Inc., 2018)Dienogest (DGN), is an orally administered synthetic progestin that has shown to have selective progesterone receptor (PR) agonistic activity and oral progestational potency on endometrium. In this paper, the investigation ... -
The redox mechanism investigation of non-small cell lung cancer drug: Erlotinib via theoretical and experimental techniques and its host–guest detection by β-Cyclodextrin nanoparticles modified glassy carbon electrode
Karadaş Bakırhan, Nurgül; Taşkın Tok, Tuğba; Özkan, Sibel Ayşıl (Elsevier B.V., 2019)Erlotinib (ERL) is a tyrosine kinase inhibitor which prevents growing of cancer cells. The electrochemical oxidation mechanism of ERL was studied in details using cyclic voltammetry. Cyclic voltammetry, differential pulse ... -
A sensitive and selective RP-LC method for the simultaneous determination of the antihypertensive drugs, enalapril, lercanidipine, nitrendipine and their validation
A RP-LC method is presented, which is sensitive and selective for the simultaneous determination of enalapril-lercanidipine and enalapril-nitrendipine binary mixtures in their pharmaceutical dosage forms. The analyte peaks ... -
Separation and elution order of the enantiomers of some beta-agonists using polysaccharide-based chiral columns and normal phase eluents by high-performance liquid chromatography
Gümüştaş, Mehmet; Özkan, Sibel Ayşıl; Chankvetadze, Bezhan (Elsevier B.V., 2016)In this study separation of enantiomers of 8 chiral ?-agonists were studied on 6 polysaccharide-based chiral columns in polar-organic and alcohol-hydrocarbon mobile phases. No separation of enantiomers was observed on any ... -
Simple and sensitive adsorptive stripping voltammetric assay of granisetron from its dosage form by platinum nanoparticles modified electrodes
Doulache, Merzak; Karadaş Bakırhan, Nurgül; Uslu, Bengi; Saidat, Boubakeur; Trari, Mohamed; Özkan, Sibel Ayşıl (Elsevier B.V., 2017)Base to the interfacial adsorptive nature of granisetron (GRN) on platinum particles modified glassy carbon electrode (PtPs/GCE). A sensitive analytical method for trace analysis of GRN based on the adsorptive stripping ... -
Simple, sensitive and reliable LC-DAD method of gemifloxacin determination in pharmaceutical dosage forms
Gümüştaş, Mehmet; Özkan, Sibel Ayşıl (2012)A sensitive, accurate, rapid, fully validated, reliable and easy method was developed for the quantification of gemifloxacin mesylate (GEM) using liquid chromatography (LC) with DAD detection. In this method; a reversed-phase ... -
Simultaneous determination and validation of emtricitabine, rilpivirine and tenofovir from biological samples using LC and CE methods
Gümüştaş, Mehmet; Çağlayan, Mehmet Gökhan; Onur, Feyyaz; Özkan, Sibel Ayşıl (John Wiley and Sons Ltd, 2018)A combination of antiretroviral agents is frequently used in effective treatment of the human immunodeficiency virus infection. In this study, two different separation methods are presented for the simultaneous determination ... -
Simultaneous determination and validation of some binary mixtures of antihypertensive drugs using ratio derivative spectrophotometric method
Kurbanoğlu, Sevinç; Gümüştaş, Mehmet; Özkan, Sibel Ayşıl (Maik Nauka Publishing / Springer SBM, 2014)Ratio derivative spectrophotometric technique is presented for the rapid, accurate and precise simultaneous determination of olmesartan medoxomil (OLM), hydrochlorothiazide (HCT), and zofenopril (ZOF) as well as HCT binary ... -
Simultaneous determination of amlodipine besylate and rosuvastatin calcium in binary mixtures by voltammetric and chromatographic techniques
Karadaş Bakırhan, Nurgül; Gümüştaş, Mehmet; Uslu, Bengi; Özkan, Sibel Ayşıl (Institute for Ionics, 2016)Voltammetric and liquid chromatographic (LC) methods have been developed for the simultaneous determination of amlodipine besylate (AML) and rosuvastatin calcium (ROS) for the first time. Detailed electrochemical behavior ... -
Simultaneous estimation of ceftazidime and ceftizoxime in pharmaceutical formulations by HPLC method
Şanlı, Senem; Şanlı, Nurullah; Gümüştaş, Mehmet; Özkan, Sibel Ayşıl; Karadaş, Nurullah; Aboul-Enein, Hassan Y. (2011)The aim of the present study was to develop a fast, sensitive and reliable method for rapid screening of cephalosporin injectable dosage forms namely ceftazidime and ceftizoxime to the detection of counterfeit and substandard ... -
A validated stability-indicating RP-LC method for the simultaneous determination of amlodipine and perindopril in tablet dosage form and their stress degradation behavior under ICH-recommended stress conditions
Gümüştaş, Mehmet; Özkan, Sibel Ayşıl (2013)A stability-indicating RP-LC assay method was developed for the simultaneous determination of the cardiovascular drugs amlodipine and perindopril in the presence of degradation products generated from forced decomposition ... -
Voltammetric and RP-LC assay for determination of benidipine HCl
The detailed electrooxidative behavior of benidipine (BEN) has been studied by using glassy carbon (GC) and boron-doped diamond (BDD) electrodes. Using cyclic voltammetry, depending on the pH values and the working electrodes, ... -
Voltammetric and RP-LC assay for the antidepressant drug mirtazapine: A validated method for the pharmaceutical dosage form
In the present paper, rapid, sensitive, selective, accurate and precise analytical methodologies were developed for the determination of the antidepressant drug mirtazapine (MIR) using voltammetry and liquid chromatography. ... -
Voltammetric behavior and determination of antidepressant drug paroxetine at carbon-based electrodes
Brycht, Mariola; Skrzypek, Slawomira; Karadaş Bakırhan, Nurgül; Smarzewska, Sylwia; Bozal Palabıyık, Burçin; Özkan, Sibel Ayşıl; Uslu, Bengi (Institute for Ionics, 2015)Simple, rapid, sensitive, and reproducible methods were developed for the assay of paroxetine in tablets. The electrooxidative behavior and determination of paroxetine on boron-doped diamond and edge plane graphite electrodes ...