Ara
Toplam kayıt 3, listelenen: 1-3
Solvent effects on pKa values of some substituted sulfonamides in acetonitrile-water binary mixtures by the UV-spectroscopy method
(2009)
The examination of the dissociation constants of sulfonamides is essential in drug-design studies and in explaining the biopharmaceutical properties of substances. The dissociation constants of ten common human and veterinary ...
Determination of dissociation constants of folinic acid (leucovorin), 5-fluorouracil, and irinotecan in hydro-organic media by a spectrophotometry method
(2010)
In this study, a multiwavelength spectrophotometry method was used for the determination of the dissociation constants of drugs used for treatment of colorectal cancer, folinic acid (leucovorin), 5-fluorouracil, and ...
Determination of pKa values of some antipsychotic drugs by HPLC-correlations with the kamlet and taft solvatochromic parameters and HPLC analysis in dosage forms
(2013)
In this study, ionization constant (pKa) values were determined by using the dependence of the retention factor on the pH of the mobile phase for four ionizable drugs, namely, risperidone (RI), clozapine (CL), olanzapine ...