Yazar "Avşar, Orçun" için Moleküler Biyoloji ve Genetik Bölümü listeleme
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Analysis of missense SNPs in the SLC47A1 and SLC47A2 genes affecting the pharmacokinetics of metformin: Computational approach
Avşar, Orçun (SPRINGERNATURE, 2022)Background: Metformin as an anti-hyperglycaemic drug is commonly used for the treatment of type 2 diabetes mellitus (T2DM). The metformin response is variable due to the interindividual variation of pharmacokinetics which ... -
In Silico Analysis of miRNA-mediated ceRNAs as Potential Molecular Biomarkers in Glioblastoma
Avşar, Orçun (2021)Objectives: Glioblastoma multiforme (GBM) is defined as the most frequent and lethal form of the primary brain tumors in the central nervous system (CNS) in adults. Recent studies have focused on the identification of the ... -
Tümör Gelişiminde ve Tedavisinde Dopamin ve Dopamin Reseptörlerinin Rolü
Avşar, Orçun (2020)Önemli bir katekolamin nörotransmitter olan dopamin, santral sinir sisteminde ve sindirim sistemi, dalak ve pankreas gibi periferik dokularda sentez edilmektedir. Hem santral sinir sisteminde hem de pe-riferal sistemde ...