Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 196, listelenen: 103-122
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HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells
(Leibniz Research Centre for Working Environment and Human Factors, 2016)Histone deacetylases (HDACs) play a major role in the regulation of chromatin structure and gene expression by changing acetylation status of histone and non-histone proteins. MS-275 (entinostat, MS) is a well-known ... -
HeLa hücrelerinde Sisplatinin MTOR, AKT, CCND1 ve STAT3 mRNA ifadesi üzerine etkileri
(Gazi Üniversitesi, 2020)Giriş: Serviks kanseri, kadınlarda gözlenen malign tümörler arasında en yaygın görülen ve kadınlarda kanser sonucu gözlenen ölümler arasında ikinci sırada bulunan önemli bir hastalıktır. Platin temelli bir bileşik olan ... -
Helmintoterapi
(Bilimsel Tıp Yayınevi, 2017)Helmintoterapi, inflamatuvar ve otoimmün hastalıkların tedavisine yardımcı olmak amacıyla konak bağışıklık sisteminin nematodlar başta olmak üzere bazı helmintlerin kullanılmasıyla uyarılmasıdır. Ülkelerin gelişmişlik ... -
Hitit Index to distinguish patients with and without Crimean-Congo hemorrhagic fever
(Elsevier Gmbh, 2019)Crimean-Congo hemorrhagic fever (CCHF) is fatal. Therefore, it is very important to use an inexpensive, easily accessible, quick and accurate screening index based on clinical signs and laboratory parameters to identify ... -
Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesinde kan kültürlerinden üreyen mikroorganizmalar ve antimikrobiyal duyarlılıkları
(Bilimsel Tıp Yayınevi, 2016)Giriş: Bakteremi ve sepsis tanısında altın standart kan kültürüdür. Kan kültürlerinde üreyen mikroorganizmaların dağılımı ve antibiyotik duyarlılıklarının belirlenmesi mortalite ve morbiditenin azaltılmasında çok önemlidir. ... -
Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesi’nde lenfadenopati ön tanılı olguların toksoplazmoz açısından irdelenmesi
(Refik Saydam Hıfzıssıhha Merkezi Başkanlığı, 2017)Amaç: Sağlıklı insanlarda genellikle asemptomatik seyreden toksoplazmozun en sık görülen semptomatik formu lokalize lenfadenopati (LAP)'dir. Bu çalışmada LAP ön tanısı ile başvuran hastaların toksoplazmoz açısından irdelenmesi ... -
Hyperemesis gravidarum affects maternal sanity, thyroid hormones and fetal health: a prospective case control study
(Springer Verlag, 2015)Purpose: Hyperemesis gravidarum (HG) is a condition of severe nausea or vomiting accompanied by various complications during pregnancy. In the present study, we aimed to demonstrate the effects of HG on mother and fetus ... -
The immunohistochemical and ultrastructural evaluation of pericytes in human full term placentas of gestasyonal diabetes mellitus
(Carbone Editore di Alessandro Pennino, 2013)Pericytes, vessel wall plays a stabilizing role in the regulation of blood flow in the microcirculation. The purpose of this study is based on non-diabetic pregnancies complicated by gestational diabetes pregnancies to ... -
The impact of anemia and body mass index (BMI) on neuromotor development of preschool children
(Associacao Medica Brasileira, 2017)Objective: According to data from the World Health Organization (WHO), anemia is a prevalent health problem that leads to increased morbidity and mortality, especially in preschool children. Anemia is recognized as a major ... -
The impact of dietary induced hyperparathyroidism on healthy and diseased periodontia: An experimental study in rats
(2012)Background and Objective Nutrition may be a potential modifying factor in periodontal conditions. The present study investigated this phenomenon for dietary induced hyperparathyroidism (dHPT) by revealing the histopathological ... -
Importance of anaplastic lymphoma kinase gene re-arrangements on non-small cell lung cancer
(Kafkas Üniversitesi Tıp Fakültesi, 2017)Despite all improvements in treatment modalities, lung cancer is the leading cause of death related to cancers worldwide. Environmental, occupational and genetic factors, as well as smoking play role in the etiology. ... -
Importance of NK Cells in Cellular and Humoral Responses Triggered by Pneumococcus Vaccination
(KARGER, 2023)Introduction: Despite the success of vaccination in reducing overall rate of pneumococcal pneumonia, Streptococcus pneumoniae is still held responsible for high mortality and modality rates worldwide. Our study aimed to ... -
In Silico Prediction of the Effects of Nonsynonymous Single Nucleotide Polymorphisms in the Human Catechol-O-Methyltransferase (COMT) Gene
(Humana Press Inc, 2020)Catechol-O-methyltransferase (COMT) enzyme performs transfer of methyl group to endogenous and exogenous catechol substrates. The COMT enzyme draws interest because of its association with psychiatric, neurological and ... -
Increased serum heme oxygenase-1 levels as a diagnostic marker of oxidative stress in preeclampsia
(Informa Healthcare, 2014)Objective: To evaluate the utility of serum biomarkers in the diagnosis of preeclampsia (PE) and also investigate possible correlation with pathogenesis of PE. Methods: Maternal serum concentrations of heme oxygenase-1 ... -
Increased serum levels of spectrin degradation products in patients with schizophrenia
(Turkish Biochemistry Society, 2018)Objective: Under various patho-physiological and physiological conditions, spectrin breakdown reactions generate several spectrin breakdown products of 120 kDa (SBDP120) and 145 kDa (SBDP145). Previous studies indicating ... -
Inductive reasoning in patients with paranoid type schizophrenia
(Bilişsel Davranışçı Psikoterapiler Derneği, 2017)Thinking patterns, reasoning and decision making processes of individuals with schizophrenia have been intriguing. The goal of our study is to evaluate the decision making and reasoning of the paranoid type schizophrenic ... -
Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy
(E-Century Publishing Corporation, 2015)Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the ... -
An interactive web application for propensity score matching with R shiny; example of thrombophilia
(2020)Aim: The aim of this study was to develop a new web-based R Shiny package that calculates propensity score using many algorithms such as logistic regression, machine learning, and performs matching analysis with balance ... -
An international bibliometric study of scientific articles on intracranial aneurysms
(Sage Publications Inc, 2021)Objectives: The number of original scientific researches on intracranial aneurysms has risen over the last 30 years. Despite the rise in the number of articles, there is no up-to-date exhaustive bibliometric research in ... -
Investigation of antioxidant activity and effect on cell viability of pyrrolidine compounds in MCF-7 (breast cancer) and DLD-1 (colon cancer) cell lines
(Al-Farabi Kazakh Natl Univ, 2021)In this study, it is aimed to investigate the effects of pyrrolidine compounds that are thought to be new drug candidates with effect on cell viability on cancer (MCF-7 and DLD-1) and normal (MCF-12A and CCD-18CO) cell ...
