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Possible association between DNA repair gene variants and cannabis dependence in a Turkish cohort: a pilot study
(Taylor and Francis Ltd., 2018)
OBJECTIVE: Substance use disorder (SUD) has important effects on health and well-being. It is well known that genetic factors play a role in SUD. The purpose of this research was to investigate whether functional variants ...
Macrophage migration inhibitory factor -173GC variant might increase the risk of behçet's disease
(S. Karger AG, 2018)
Objective: The aim of the present study was to investigate any possible association between the macrophage migration inhibitory factor (MIF) -173GC variant and Behçet's disease (BD) in a group of Turkish patients. Subjects ...
Association of the TNF-α, IL-2, and IL-2RB gene variants with susceptibility to psoriasis in a Turkish cohort
(Termedia Publishing House Ltd., 2018)
Aim of the study: The aim of this study was to investigate the role TNF-α, IL -2, and IL -2RB variants in psoriasis (Ps) and to evaluate the association between these variants and clinical features. Material and methods: ...
Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
(Iranian Society of Nephrology, 2018)
Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ...
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
(John Wiley and Sons Inc., 2018)
Background: Temporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ...
XRCC4 rs6869366 polymorphism is associated with susceptibility to both nicotine dependence and/or schizophrenia
(Universidade de Sao Paulo, 2018)
Background: Oxidative stress induced DNA damage has been assumed to contribute to the etiopathogenesis of schizophrenia (Sch). Smoking prevalence was more common in patients with Sch. The X-ray repair cross-complementation ...
CYP2A6 gene variants may explain smoking status in a Turkish cohort
(Taylor and Francis Ltd., 2018)
OBJECTIVE: Nicotine is the main addictive agent present in tobacco and is principally metabolized by a cytochrome P450-mediated oxidation process. While smoking patterns differ widely among smokers, the metabolization rate ...