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Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids

Date

2016

Author

Uludağ, Nesimi
Yılmaz, Recep
Asutay, Oktay
Çolak, Naki

Metadata

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Citation

Uludag, N., Yılmaz, R.K., Asutay, O., Çolak, N. (2016). Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids. Chemistry of Heterocyclic Compounds, 52(3), 196-199.

Abstract

[Figure not available: see fulltext.]A new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps. © 2016, Springer Science+Business Media New York.

Source

Chemistry of Heterocyclic Compounds

Volume

52

Issue

3

URI

https://doi.org/10.1007/s10593-016-1860-4
https://hdl.handle.net/11491/492

Collections

  • Makale Koleksiyonu
  • Scopus İndeksli Yayınlar Koleksiyonu
  • WoS İndeksli Yayınlar Koleksiyonu



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