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Toplam kayıt 24, listelenen: 1-10
Association of XRCC1 and XPD functional gene variants with nicotine dependence and/or schizophrenia: a case-control study and in silico analysis
(Taylor and Francis Ltd., 2019)
OBJECTIVE: The role of DNA repair mechanisms has received attention recently in schizophrenia (Sch). Sch patients show an increased prevalence of nicotine dependence (ND). This study aimed to find out whether functional ...
Possible association between DNA repair gene variants and cannabis dependence in a Turkish cohort: a pilot study
(Taylor and Francis Ltd., 2018)
OBJECTIVE: Substance use disorder (SUD) has important effects on health and well-being. It is well known that genetic factors play a role in SUD. The purpose of this research was to investigate whether functional variants ...
CNR2 rs2229579 and COMT Val158Met variants, but not CNR2 rs2501432, IL-17 rs763780 and UCP2 rs659366, contribute to susceptibility to substance use disorder in the Turkish population
(Taylor & Francis Ltd, 2019)
OBJECTIVE: Substance use disorders (SUD) are among the most important public health problems throughout the world. We investigated whether COMT (Val108/158Met), CNR2 (rs2501432 and rs2229579), UCP2 (rs659366), and IL-17 ...
PER3 VNTR variant and susceptibility to smoking status/substance use disorder in a Turkish population
(Univ Sao Paulo, Inst Psiquiatria, 2020)
Background: Substance use and smoking exert devastating impact on sleep, especially hindering the ease of falling asleep, compromising the sleep maintenance, and distorting the sleep cycles. PERIOD genes are believed to ...
The miRNA 196a2 rs11614913 variant has prognostic impact on Turkish patients with multiple myeloma
(Springernature, 2020)
Objective Multiple myeloma (MM) arises from malignant plasma cells as a single clone in the bone marrow. Accumulating evidences have reported that there is an association between miR-196a2 (rs11614913) variant and various ...
TNF-alpha-308 G/A variant may be associated with bipolar disorder in a Turkish population
(Univ Sao Paulo, Inst Psiquiatria, 2020)
Background: Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory multifunctional cytokine produced by macrophages. A dysregulation of the immune system contribute to the pathogenesis of bipolar disorder (BD). In ...
Medication-related osteonecrosis of the jaw (MRONJ) and eNOS Polymorphisms in multiple myeloma patients: a single center experience
(Bmc, 2021)
Background Multiple myeloma (MM) constitutes approximately 10% of hematological malignancies. Bisphosphonates have established themselves in solid organ metastasis and multiple myeloma lytic bone lesions by inhibiting ...
What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?
(Springer, 2021)
Background In today's practice, gene-based approaches come to the fore in the determination of prognosis and treatment preferences of multiple myeloma (MM). DNA methylation is one of the new approach parameters. DNA ...
Cytokine gene variants/expressions and non-syndromic microtia – Is there a link?
(Continuing Education, and Scientific Research Association (CESRA), 2017)
Sitokin gen varyantları/ekspresyonları ve non-sendromik mikrotia - Bir ilişki var mıdır?Amaç: Mikrotianın etyopatogenezinde birçok genetik ve çevreselfaktörler araştırılmasına rağmen hala belirsizlik vardır. Bu çalışmadabir ...
The roles of endothelial nitric oxide synthase (eNOS) and myeloperoxidase (MPO) genes in microtia
(Deomed Publishing, 2016)
Objective:The aim of this study was to determine the relationshipbetween polymorphisms of endothelial nitric oxide synthase (eNOS)and myeloperoxidase (MPO) genes and development of microtia. Methods:Nineteen (11 males, 8 ...