Yazar "Nursal, Ayse Feyda" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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CNR2 rs2229579 and COMT Val158Met variants, but not CNR2 rs2501432, IL-17 rs763780 and UCP2 rs659366, contribute to susceptibility to substance use disorder in the Turkish population
Kurnaz, Selin; Yazici, Ahmet Bulent; Nursal, Ayse Feyda; Aydin, Pinar Cetinay; Atar, Ayca Ongel; Aydin, Nazan; Pehlivan, Sacide (Taylor & Francis Ltd, 2019)OBJECTIVE: Substance use disorders (SUD) are among the most important public health problems throughout the world. We investigated whether COMT (Val108/158Met), CNR2 (rs2501432 and rs2229579), UCP2 (rs659366), and IL-17 ... -
eNOS and VEGF Variants Might Increase the Risk of Pancreatic Cancer
Hasan Dagmura; Yigit, Serbulent; Gumusay, Ozge; Nursal, Ayse Feyda; Daldal, Emin; Karakus, Nevin (Pleiades Publishing Inc, 2021)Background: Endothelial nitric oxide synthase (eNOS) is essential in chronic inflammation and carcinogenesis. The association between variants in vascular endothelial growth factor (VEGF) and several cancers still remains ... -
Global and glucocorticoid receptor gene-specific (NR3C1) DNA methylation analysis in patients with cannabinoid or synthetic cannabinoid use disorder
Pehlivan, Sacide; Aytac, Hasan Mervan; Aydin, Pinar Cetinay; Nursal, Ayse Feyda; Pehlivan, Mustafa (Elsevier Ireland Ltd, 2021)This study investigates the relationship between cannabinoid use disorder (CUD) or synthetic cannabinoid use disorder (SCUD) and the global methylation, methylation of NR3C1 gene promotor, and NR3C1 BclI poly-morphism, ... -
Impact of Endothelial NOS VNTR Variant on Susceptibility to Diabetic Neuropathy and Type 2 Diabetes Mellitus
Yigit, Serbulent; Nursal, Ayse Feyda; Uzun, Suheyla; Rustemoglu, Husniye; Dashatan, Payam Amiri; Soylu, Huseyin; Karakus, Nevin (Bentham Science Publ Ltd, 2021)Purpose: The aim of this study was to evaluate whether the VNTR intron 4b/4a variant in the eNOS gene is associated with type 2 diabetes mellitus (T2DM) and DPN. Methods: A total of 598 subjects were enrolled in the study. ... -
The Impact of PER3 VNTR Polymorphism on the Development of Schizophrenia in a Turkish Population
Ozsoy, Filiz; Yigit, Serbulent; Nursal, Ayse Feyda; Kulu, Muberra; Karakus, Nevin (Pleiades Publishing Inc, 2021)Introduction: Up to 80% of patients who suffer from schizophrenia have sleep impairments, which affect physical and mental health, as well as quality of life. Several tandem repeat polymorphisms (VNTRs) in the Period 3 ... -
Medication-related osteonecrosis of the jaw (MRONJ) and eNOS Polymorphisms in multiple myeloma patients: a single center experience
Tas Ozyurtseven, Betul; Serin, Istemi; Nursal, Ayse Feyda; Pehlivan, Sacide; Pehlivan, Mustafa (Bmc, 2021)Background Multiple myeloma (MM) constitutes approximately 10% of hematological malignancies. Bisphosphonates have established themselves in solid organ metastasis and multiple myeloma lytic bone lesions by inhibiting ... -
The miRNA 196a2 rs11614913 variant has prognostic impact on Turkish patients with multiple myeloma
Kirik, Melya Pelin; Pehlivan, Mustafa; Nursal, Ayse Feyda; Oyaci, Yasemin; Pehlivan, Sacide; Serin, Istemi (Springernature, 2020)Objective Multiple myeloma (MM) arises from malignant plasma cells as a single clone in the bone marrow. Accumulating evidences have reported that there is an association between miR-196a2 (rs11614913) variant and various ... -
PER3 VNTR variant and susceptibility to smoking status/substance use disorder in a Turkish population
Nursal, Ayse Feyda; Aydin, Pinar Cetinay; Uysal, Mehmet Atilla; Pehlivan, Mustafa; Oyac, Yasemin; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Substance use and smoking exert devastating impact on sleep, especially hindering the ease of falling asleep, compromising the sleep maintenance, and distorting the sleep cycles. PERIOD genes are believed to ... -
Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer
Dagmura, Hasan; Yigit, Serbulent; Nursal, Ayse Feyda; Duman, Esra; Gumusay, Ozge (Mary Ann Liebert, Inc, 2021)Objective: Pancreatic cancer (PC) is a serious disease with poor outcomes, and its prevalence has been increasing steadily. The circadian rhythm (CR) is involved in multiple physiological events and maintains homeostasis. ... -
Role of MIF-173G/C and Mbl2 Codon 54A/B Variants in the Risk of Multiple Myeloma: An Association Study
Pehlivan, Mustafa; Nursal, Ayse Feyda; Gundes, Ilknur; Oyaci, Yasemin; Kivanc, Demet; Pehlivan, Sacide (Bentham Science Publ Ltd, 2021)Background: Multiple myeloma (MM) is a malignant disease manifested by the clonal proliferation of atypical plasma cells. Macrophage inhibitory factor (MIF) is one of the pleiotropic regulators in various biological and ... -
TNF-alpha-308 G/A variant may be associated with bipolar disorder in a Turkish population
Nursal, Ayse Feyda; Aytac, Hasan Mervan; Ciftci, Hayriye Senturk; Yazar, Menekse Sila; Oyaci, Yasemin; Pehlivan, Mustafa; Pehlivan, Sacide (Univ Sao Paulo, Inst Psiquiatria, 2020)Background: Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory multifunctional cytokine produced by macrophages. A dysregulation of the immune system contribute to the pathogenesis of bipolar disorder (BD). In ... -
What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?
Pehlivan, Sacide; Serin, Istemi; Nursal, Ayse Feyda; Oyaci, Yasemin; Gundes, Ilknur; Pehlivan, Mustafa (Springer, 2021)Background In today's practice, gene-based approaches come to the fore in the determination of prognosis and treatment preferences of multiple myeloma (MM). DNA methylation is one of the new approach parameters. DNA ...