Yazar "Önen, İlke Hacer" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Effects of EF-24, RAD001, and paclitaxel on the expression profiles of apoptotic and anti-apoptotic genes
Alp, Ebru; Yılmaz, Akın; Önen, İlke Hacer; Menevşe, Emine Sevda (Wolters Kluwer - Medknow, 2017)Context: Cancer cells exert differential responses to chemotherapeutics and inhibitors. To the best of our knowledge, a few or no research has been performed until now to determine the effect of EF-24 and RAD001 on MDA-MB-231 ... -
HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells
Yar Sağlam, Atiye Seda; Yılmaz, Akın; Önen, İlke Hacer; Alp, Ebru; Kayhan, Handan; Ekmekci, Abdullah (Leibniz Research Centre for Working Environment and Human Factors, 2016)Histone deacetylases (HDACs) play a major role in the regulation of chromatin structure and gene expression by changing acetylation status of histone and non-histone proteins. MS-275 (entinostat, MS) is a well-known ... -
Reduced BCL2 and CCND1 mRNA expression in human cervical cancer HeLa cells treated with a combination of everolimus and paclitaxel
Yılmaz, Akın; Alp, Ebru; Önen, İlke Hacer; Menevşe, Emine Sevda (Termedia Publishing House Ltd., 2016)Aim of the study: Cervical cancer is the second most common malignancy in women worldwide. Everolimus displays direct effects on growth and proliferation of cancer cells via inhibition of mammalian target of rapamycin ...