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dc.contributor.authorKoseoglu, Derya
dc.contributor.authorOzdemir Baser, Ozden
dc.contributor.authorCetin, Zeynep
dc.date.accessioned2021-11-01T15:05:50Z
dc.date.available2021-11-01T15:05:50Z
dc.date.issued2021
dc.identifier.issn8755-1039
dc.identifier.issn1097-0339
dc.identifier.urihttps://doi.org/10.1002/dc.24823
dc.identifier.urihttps://hdl.handle.net/11491/7419
dc.description.abstractBackground The clinical management of Bethesda III category thyroid nodules has some undefined points and differs among centers and conflicting malignancy rates are present in the literature. The aim of this study was to investigate the Bethesda category III thyroid nodule outcomes in our centers, to determine malignancy rates and also to evaluate clinical and sonographic features which may help to predict malignancy. Methods This retrospective study included 333 patients with thyroid nodules who had Bethesda category III on fine needle aspiration (FNA) in three tertiary medical centers of Turkey. Results Among 333 patients, 302 had appropriate follow up. Eighteen patients received thyroidectomy after the first FNA, with a malignancy rate of 38.89% (7/18) and 284 patients received a second FNA. After the second FNA, thyroidectomy was performed in 80 patients and 41 patients needed the third FNA. Thirteen thyroidectomies were performed after the third FNA. Totally 111 patients received thyroidectomy with a malignancy rate of 48.65% (54/111) among patients with surgery and the lower bound was detected as 17.88% (54/302). Of these patients the malignancy rates of patients receiving thyroidectomy with two and three FNAs were 47.50% (38/80) and 69.23% (9/13), respectively. Hypoechogenicity, microcalcification, and irregular margin were found as good predictors for malignancy. Conclusion We demonstrated that the malignancy rate was 48.65% in patients receiving thyroidectomy. We showed a higher malignancy rate than the traditionally rate of 5%-15%. This study showed that repeat FNAs decrease the rate of unnecessary surgery performed for benign lesions by increasing the rate of malignancy detection.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofDiagnostic Cytopathologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBethesda III categoryen_US
dc.subjectfine needle aspirationen_US
dc.subjectmalignancyen_US
dc.subjectpapillary thyroid carcinomaen_US
dc.subjectthyroid noduleen_US
dc.titleMalignancy outcomes and the impact of repeat fine needle aspiration of thyroid nodules with Bethesda category III cytology: A multicenter experienceen_US
dc.typearticleen_US
dc.department[Belirlenecek]en_US
dc.authoridcetin, zeynep / 0000-0001-7824-4644
dc.identifier.volume49en_US
dc.identifier.issue10en_US
dc.identifier.startpage1110en_US
dc.identifier.endpage1115en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.department-temp[Koseoglu, Derya] Hitit Univ, Dept Endocrinol & Metab, Fac Med, Buharaevler Mah Buhara 5 Cad 34-12, TR-19400 Corum, Turkey; [Ozdemir Baser, Ozden] Yozgat State Hosp, Dept Endocrinol & Metab, Yozgat, Turkey; [Cetin, Zeynep] Amasya Univ, Dept Endocrinol & Metab, Fac Med, Amasya, Turkeyen_US
dc.contributor.institutionauthor[Belirlenecek]
dc.identifier.doi10.1002/dc.24823
dc.description.wospublicationidWOS:000668543500001en_US
dc.description.scopuspublicationid2-s2.0-85109019440en_US
dc.description.pubmedpublicationidPubMed: 34196509en_US


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