Assessment of the Relationship Between Serum Vitamin D Levels and Obesity in the Reproductive-Aged Women

Abstract

Objectives: The aim of this study was to examine the association between Vitamin D levels and body mass index (BMI) as an adiposity measure in the reproductive-aged women. Methods: A total of 171 women were included in this comparative cross-sectional study. The subjects were classified into three groups according their BMI’s: Group I; non-obese=80 (BMI<25.0 kg/m2 ), Group II; overweight=54 (25.0<BMI<30 kg/m2 ), and Group III; obese=37 (BMI>30 kg/m2 ). Results: Obese women possessed the lowest mean follicle stimulating hormone levels (6.26±1.46, p=0.001), and the highest luteinizing hormone (LH) levels were found in non-obese group (5.70±2.15, p=0.001). The comparison of antiMüllerian hormone (AMH) levels yielded that there was a significant difference between non-obese and overweight women (4.96±4.02 vs. 3.11±3.03, p=0.019). The mean Vitamin D level was found to be highest in the non-obese group (10.45±7.48, p=0.043). The correlation analysis demonstrated that Vitamin D level was weak correlated with AMH level in the overweight group (r=0.285, p=0.047). Conclusion: Our study showed a negative association between Vitamin D level and obesity. Vitamin D supplementation may aid to reduce the obesity incidence. Further evaluations are needed to elucidate this issue.