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dc.contributor.authorArduç, Ayşe
dc.contributor.authorAyçiçek Doğan, Berçem
dc.contributor.authorÖzuǧuz, Ufuk
dc.contributor.authorTuna, Mazhar Müslüm
dc.contributor.authorGökay, Ferhat
dc.contributor.authorAteş Tütüncü, Yasemin
dc.contributor.authorIşık, Serhat
dc.contributor.authorAydın, Yusuf
dc.contributor.authorPeksoy, İrfan
dc.contributor.authorBerker, Dilek
dc.contributor.authorGüler, Serdar
dc.date.accessioned2019-05-13T08:57:20Z
dc.date.available2019-05-13T08:57:20Z
dc.date.issued2014
dc.identifier.citationArduç, A., Ayçiçek Doğan, B., Özuğuz, U., Tuna, M. M., Gökay, F., Ateş Tütüncü, Y., Işık, S., Aydın, Y.[et.al.]. (2014). The effect of radioactive iodine treatment on 14C urea breath test results in patients with hyperthyroidism. Clinical Nuclear Medicine, 39(12), 1022-1026.en_US
dc.identifier.issn0363-9762
dc.identifier.urihttps://doi.org/10.1097/RLU.0000000000000519
dc.identifier.urihttps://hdl.handle.net/11491/903
dc.description.abstractPurpose: Radioactive 131Iodine therapy (RAIT) plays a major role in the treatment of hyperthyroidism. In addition to the thyroid gland, significant amounts of radioactive iodine are maintained in the stomach. The aim of this study was to determine if RAIT has any effect on Helicobacter pylori infection, based on the 14C urea breath test (UBT). Materials and Methods: The study included 85 patients with hyperthyroidism scheduled to undergo RAIT and 69 hyperthyroid subjects in whom methimazole treatment was planned. All subjects had pretreatment-positive UBT results, and the test was repeated on the first and third months after RAIT and methimazole treatment. Results: After a mean RAIT dose of 15 mCi (range, 10Y20 mCi), UBT became negative in 13 (15.3%) of 85 patients on the first month and 18 (21.2%) of 85 patients on the third month. All subjects treated with methimazole remained UBT positive on the first and third months of methimazole treatment (100%). Reduction in the number of UBT-positive patients on both the first and the third months after RAITwas statistically significant (P G 0.001). Distribution of hyperthyroidism etiologies and thyroid autoantibody levels in subjects with UBT that became negative and in subjects with UBT that remained positive were similar in the RAIT group (P 9 0.05). Urea breath test negativity rates did not differ according to the radioiodine dose. Conclusions: Our findings indirectly showed that RAIT might have an antimicrobial effect on H. pylori. Clinical applications of this beneficial effect of RAITon H. pylori should be further evaluated. Copyright © 2014 by Lippincott Williams & Wilkins.en_US
dc.language.isoeng
dc.publisherLippincott Williams and Wilkinsen_US
dc.relation.isversionof10.1097/RLU.0000000000000519en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject14C Urea Breath Testen_US
dc.subjectHelicobacter Pylorien_US
dc.subjectHyperthyroidismen_US
dc.subjectRadioactive Iodine Therapyen_US
dc.titleThe effect of radioactive iodine treatment on 14C urea breath test results in patients with hyperthyroidismen_US
dc.typearticleen_US
dc.relation.journalClinical Nuclear Medicineen_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.identifier.volume39en_US
dc.identifier.issue12en_US
dc.identifier.startpage1022en_US
dc.identifier.endpage1026en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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