Investigation of dna binding and cleavage activities of boron complexes in the presence of hydrogen peroxide
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info:eu-repo/semantics/closedAccessDate
2014Author
Devrim, Alparslan KadirArslantaş, Ali
Sudağıdan, Mert
Köse, Dursun Ali
Zümreoğlu Karan, Birgül
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Devrim, A. K., Arslantaş, A., Sudağıdan, M., Köse, D. A., Karan, B. (2014). Investigation of dna binding and cleavage activities of boron complexes in the presence of hydrogen peroxide. Studia Universitatis Babes-Bolyai Chemia, 59(3), 109-118.Abstract
Magnesium [di(hydroxy)mono(citratoborate)]dihydrate (Mg[B(Cit)(OH)2]2.2H2O), Lithium [di(hydroxy)mono(citratoborate)]hydrate Li[B(Cit)(OH)2].H2O, Sodium [di(hydroxy)mono(salicylato) borate)hydrate Na[B(Sal)(OH)2].H2O and Magnesium[bis(salicylatoborate)]decahydrate Mg[B(Sal)2]2.10H2O) complexes have been synthesized and characterized. The cattle genomic DNA (CG-DNA) interaction of the complexes was studied by spectroscopic methods, viscosity, and electrophoresis measurements. The complexes partially intercalated to CG-DNA. Furthermore, DNA cleavage activity of these complexes was also investigated using agarose gel electrophoresis and the complexes show moderate ability of cleavage to the DNA
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Studia Universitatis Babes-Bolyai ChemiaVolume
59Issue
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