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Toplam kayıt 198, listelenen: 1-20
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Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
(2008)In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ... -
Sıçan serebellumunda demir nörotoksisitesine karşı vitamin E'nin koruyucu etkisi
(Fırat Üniversitesi, 2009)Amaç: Bu çalışmada, intraserebroventriküler olarak verilen demirin, sıçan serebellar Purkinje hücrelerinde oluşturduğu nörotoksisiteye karşı yağda çözülebilen güçlü bir antioksidan olan vitamin E'nin (?-tokoferol) etkisini ... -
Demirin neden olduğu purkinje hücre kaybı üzerine nitrik oksit sentaz inhibisyonunun koruyucu etkisi
(2009)Amaç: Demir, nöronal hiperaktivite ve oksidatif stresi indüklemek için sıklıkla kullanılan bir metaldir. Nitrik oksit sentaz (NOS) tarafından sentezlenen nitrik oksit ile hücre ölümü arasındaki ilişkiyi ortaya koyan bulgular ... -
Iron-induced cerebellar purkinje cell loss is ameliorated by flunarizine
(Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TÜBİTAK), 2009)Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkinje cells in rats and the possible neuroprotective effect of flunarizine, a ... -
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: The role of opioid receptors
(Lippincott Williams and Wilkins, 2009)BACKGROUND: In comparison with cutaneous pain, the role of ?2-adrenoceptor (?2-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on ... -
Alpha-tocopherol decreases iron-induced hippocampal and nigral neuron loss
(2010)There are many studies about iron-induced neuronal hyperactivity and oxidative stress. Some reports also showed that iron levels rise in the brain in some neurodegenerative diseases such as Parkinson’s (PD) and Alzheimer’s ... -
Analiz öncesi (preanalitik) hata kaynakları ve eğitimin hata önlemedeki rolü
(Dicle Üniversitesi Tıp Fakültesi, 2012)Amaç: Bu çalışmada, biyokimya ve mikrobiyoloji laboratuarlarına gönderilen örneklerde preanalitik hataların analizi ve eğitimin hata önlemedeki rolü incelenmiştir. Gereç ve yöntem: Sekiz aylık dönem boyunca merkez laboratuarına ... -
Determining the factors that affect burnout and job satisfaction among academicians a sample application on the Hitit University
(Uluslararası Balkan Üniversitesi, 2012)Academicians are the most important components of the universities. Therefore, aim of this study is to identify the burnout and job satisfaction levels of academic personnel in Hitit University, and to evaluate the ... -
The impact of dietary induced hyperparathyroidism on healthy and diseased periodontia: An experimental study in rats
(2012)Background and Objective Nutrition may be a potential modifying factor in periodontal conditions. The present study investigated this phenomenon for dietary induced hyperparathyroidism (dHPT) by revealing the histopathological ... -
Çorum ilindeki liselerin 2012-2013 eğitim öğretim sürecindeki etkinliğinin veri zarflama analizi ile ölçülmesi
(Hitit Üniversitesi, 2013)Bu çalışmanın temel amacı Çorum ilindeki liselerin 2012-2013 eğitim-öğretim sürecindeki göreli etkinliklerinin Veri Zarflama Analizi (VZA) tekniği ile hesaplanması ve elde edilen bulgular sonucunda okulların etkinliğini ... -
Laboratuvar fare, sıçan ve kobaylarında dışkı bakısı ile helmintlerin araştırılması
(Etlik Veteriner Kontrol Merkez Araştırma Enstitüsü, 2013)Laboratuvar fare, sıçan ve kobaylarında helmint enfeksiyonlarının yaygınlığını tespit etmek amacıyla dışkı örnekleri yüzdürme yöntemiyle incelenmiştir. Çalışma 536 Sprag-Dawley, 265 Wistar Albino, 48 Long-Evans olmak üzere ... -
The immunohistochemical and ultrastructural evaluation of pericytes in human full term placentas of gestasyonal diabetes mellitus
(Carbone Editore di Alessandro Pennino, 2013)Pericytes, vessel wall plays a stabilizing role in the regulation of blood flow in the microcirculation. The purpose of this study is based on non-diabetic pregnancies complicated by gestational diabetes pregnancies to ... -
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity: The role of L-type calcium channels in iron-induced neurotoxicity
(Informa Healthcare, 2013)Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ... -
Capillaria hhepatica in mouse (Apodemus flavicollis) from Giresun province of Turkey
(Türkiye Parazitoloji Derneği, 2014)Capillaria hepatica is a nematode with worldwide distribution, which can cause parasitic hepatitis both in animals and humans. A mouse (Apodemus flavicollis), trapped in Giresun Province was diagnosed as having capillariasis ... -
A preliminary study of the contribution of telemicroscopy to the diagnosis and management of skin tumours in teledermatology
(Royal Society of Medicine Press Ltd, 2014)Dermatology images can be acquired using a miniature handheld digital microscope at magnifications of 10- to 30-fold. We investigated the contribution of telemicroscopy to the reliability and accuracy of teledermatology ... -
Onkoloji Hastalarında Hiponatremi Sıklığı ve Sağ Kalımla İlişkisi
(2014)Amaç: Hiponatremi; asemptomatik seyredebilen, birçok hastalıkla birlikte bulunabilen nörolojik bozukluklara yol açarak mortalite hızını arttırabilen bir klinik durumdur. Kanser hastalarında kanserin kendisine ya da ... -
Correlation between iron stores and QTc dispersion in chronic ambulatory peritoneal dialysis patients
(Informa Healthcare, 2014)Aim: We aimed to investigate the QT dispersion and corrected QT (QTc) dispersion which are suggested as the signals of ventricular arrhythmias, in patients on maintenance CAPD and to evaluate the correlation between iron ... -
The comparison of endogenous angiogenesis inhibitors in normotensive and preeclamptic placentas: An immunohistochemical study
(Informa Healthcare, 2014)Objective: Recently, it has been reported that endogenous angiogenesis inhibitors play a key role in the pathophysiology of preeclampsia. Thrombospondin-1, angiostatin and vasostatin are endogenous angiogenesis inhibitors ... -
Increased serum heme oxygenase-1 levels as a diagnostic marker of oxidative stress in preeclampsia
(Informa Healthcare, 2014)Objective: To evaluate the utility of serum biomarkers in the diagnosis of preeclampsia (PE) and also investigate possible correlation with pathogenesis of PE. Methods: Maternal serum concentrations of heme oxygenase-1 ... -
Serum amyloid A, fetuin-A, and pentraxin-3 levels in patients with ischemic stroke: Novel prognostic biomarkers?
(Turkiye Klinikleri Journal of Medical Sciences, 2014)Aim: Inflammation plays an important role in acute ischemic stroke. In this study we aimed to investigate the relationship between acute ischemic stroke and serum amyloid A, fetuin-A, and pentraxin-3 which are inflammation ...
