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    A functional tool demonstrating the physical function decline independent of age in patients with predialysis chronic kidney disease
    (Turkiye Klinikleri Journal of Medical Sciences, 2017) Taşoğlu, Özlem; Bayrakcı, Nergiz; Özcan, Didem Sezgin; Özkayar, Nihal; Taşoğlu, İrfan; Özgirgin, Neşe
    Background/aim: Physical function decline in chronic kidney disease (CKD) patients has been a popular area of investigation in the last decade. It has been shown that lower levels of physical function in CKD results in poor outcomes. Nevertheless, nephrology practice does not include routine assessment of physical function. The aim of the present study is to elucidate which physical function assessment tool is better in CKD. Materials and methods: A total of 148 predialysis CKD patients and 40 healthy controls were included in this cross-sectional single-blind study. CKD patients were further divided into two groups as stage 3 and stage 4/5. A hand dynamometer, the Short Physical Performance Battery (SPPB), and the Timed Up and Go Test (TUGT) were applied to all study participants. Results: All physical function tests were significantly different between study and control groups. In multivariate analysis the SPPB (P < 0.001) emerged as an independent variable in CKD group. Conclusion: The SPPB is a promising, easily applicable, inexpensive, and sensitive tool that can indicate functional decline independent of age in predialysis CKD patients and can be used in clinical practice to monitor these patients. © TÜBİTAK.
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    Is thyroid function associated with masked hypertension?
    (Turkish Society of Cardiology, 2016) Ateş, İhsan; Altay, Mustafa; Kaplan, Mustafa; Arıkan, Mehmet Fettah; Özkayar, Nihal; Alagüney, Mehmet Erdem; Dede, Fatih; Özkara, Adem
    Masked hypertension (MHT) was first defined by Pickering in 1992, and its importance is progressively increasing (1). MHT is a condition wherein blood pressure measured according to hypertension guidelines in office is normal, whereas the mean 24-h ambulatory blood pressure measurement or blood pressure measurement out of office is high (2). Studies relating to the etiology of MHT is limited, and possible etiological factors include work stress, smoking, alcohol use, male sex, and excessive physical activity (3, 4). The association between MHT and thyroid hormone, which has major effects on the cardiovascular system, is not known. This study aims to investigate the association between thyroid hormone and blood pressure in newly diagnosed MHT patients
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    Microscopic Polyangiitis Nodosa: A Rare Cause of Cerebral Hemorrhage
    (2019) Eser, Barış; Koyun, Osman Nuri; Doğan, İbrahim; Şahin, Mustafa; Çolak, Aysel; Özkayar, Nihal
    Microscopic polyangiitis nodosa (MPA) is a necrotizing vasculitis that affects small vessels, typically associated with myeloperoxidase anti-neutrophil cytoplasmic antibody. Cerebrovascular diseases are rarely reported to be associated with MPA. A 41-year-old male patient presented to the emergency room with complaints of speech difficulty and loss of strength on the left upper extremity, and MPA was detected with cerebral hemorrhage and renal failure. The case report, just as we first defined with this case in the national literature, was presented to emphasize that MPA may be rarely demonstrated with symptoms of cerebrovascular involvement except for commonly seen organ involvement.
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    Relationship between socioeconomic level, and the prevalence of masked hypertension and asymptomatic organ damage
    (International Scientific Information, Inc., 2015) Ateş, İhsan; Altay, Mustafa; Kaplan, Mustafa; Özkayar, Nihal; Toprak, Güvenç; Alagüney, M. Erdem; Özkara, Adem
    Background: This study aimed to determine the prevalence of masked hypertension (MHT) and its association with asymptomatic organ damage (AOD) in a low socioeconomic district of Ankara, Turkey. Material/Methods: We retrospectively reviewed data obtained from the medical records of 712 patients with no known diagnosis of hypertension who presented to a polyclinic due to symptoms related to elevated blood pressure (BP) and were screened for MHT. Essential hypertension (EHT) existed in 86 patients screened for AOD. The presence of AOD in patients diagnosed with MHT and EHT was recorded. Results: Among the 712 patients, 206 were diagnosed with EHT. Among the remaining 506 patients, 73 were diagnosed with MHT. The patients with MHT had significantly higher left ventricular mass index, carotid intima-media thickness, and 24-h urinary microalbuminuria level (all indicators of AOD) than those with EHT. Conclusions: A significantly higher percentage of patients with MHT had AOD, as compared to those with EHT, in a low socioeconomic district of Ankara. Based on this finding, patients who present with hypertensive symptoms but have a normal BP should be advised to measure their BP at home. © Med Sci Monit, 2015.
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    The association between hope, anxiety, depression, coping strategies and perceived social support in patients with chronic kidney disease
    (2019) Yücens, Bengü; Kotan, Vahap Ozan; Özkayar, Nihal; Kotan, Zeynep; Yüksel, Rabia; Bayram, Şenol; Göka, Erol
    Objective: Patients with chronic kidney disease (CKD) may experience psychiatric problems while having to cope with the various characteristics of the disease. Identifying the level of hope, coping strategies, and perceived social support may provide valuable information to improve treatment plans and the response to treatment. This study aimed to evaluate the association between hope, anxiety, depression, coping strategies, and perceived social support in patients with CKD. Method: A total of 65 grade 3 or 4 CKD patients and a healthy control group (51 volunteers) with matched baseline sociodemographic characteristics were included. The participants were evaluated using a sociodemographic data form, the Herth Hope Scale (HHS), Hospital Anxiety Depression Scale (HADS), COPE Inventory, and the Multidimensional Scale of Perceived Social Support (MSPSS). Results: The level of hope was lower, depression scores were higher and non-functional coping strategies were observed more often in patients with CKD compared to the healthy control group. In multiple linear regression analysis, anxiety and depression levels were found to have a negative effect and perceived social support by the family a positive effect on the level of hope in patients with CKD. Conclusion: Anxiety, depression, and perceived social support by the family predict the hope level of patients with CKD. A multidisciplinary approach including psychiatric consultation should be adopted in the treatment of patients with CKD as hope plays an important role in treatment compliance.
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    The association between hope, anxiety, depression, coping strategies and perceived social support in patients with chronic kidney disease
    (Yerkure Tanitim ve Yayincilik Hizmetleri A.S., 2019) Yücens, Bengü; Kotan, Vahap Ozan; Özkayar, Nihal; Kotan, Zeynep; Yüksel, Rabia Nazik; Bayram, Şenol; Dede, Fatih; Göka, Erol
    Objective: Patients with chronic kidney disease (CKD) may experience psychiatric problems while having to cope with the various characteristics of the disease. Identifying the level of hope, coping strategies, and perceived social support may provide valuable information to improve treatment plans and the response to treatment. This study aimed to evaluate the association between hope, anxiety, depression, coping strategies, and perceived social support in patients with CKD. Method: A total of 65 grade 3 or 4 CKD patients and a healthy control group (51 volunteers) with matched baseline sociodemographic characteristics were included. The participants were evaluated using a sociodemographic data form, the Herth Hope Scale (HHS), Hospital Anxiety Depression Scale (HADS), COPE Inventory, and the Multidimensional Scale of Perceived Social Support (MSPSS). Results: The level of hope was lower, depression scores were higher and non-functional coping strategies were observed more often in patients with CKD compared to the healthy control group. In multiple linear regression analysis, anxiety and depression levels were found to have a negative effect and perceived social support by the family a positive effect on the level of hope in patients with CKD. Conclusion: Anxiety, depression, and perceived social support by the family predict the hope level of patients with CKD. A multidisciplinary approach including psychiatric consultation should be adopted in the treatment of patients with CKD as hope plays an important role in treatment compliance. © 2019 Yerkure Tanitim ve Yayincilik Hizmetleri A.S. All Rights Reserved.