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    Different Aspects on Clinical Presentation of Developmental Venous Anomalies: Are They as Benign as Known? A Single Center Experience
    (Elsevier, 2021) Kurt, Gokhan; Aslan, Ayfer; Kara, Enes; Erol, Gokberk; Sahin, Merve Buke; Ucar, Murat
    Background: Cerebral developmental venous anomalies (DVAs) are frequently diagnosed incidentally owing to the advances in neuroimaging. They are regarded as clinically insignificant due to their supposed quiescent existence which the authors aimed to contradict in this paper. Aim: In the aim of constituting a better understanding of clinical presentation of DVAs and making an estimation regarding the probability of resulting in a hemorrhage, the authors presented their experiences with a case series of DVAs. Methods: A retrospective analysis was carried out among patients who underwent brain MRI in a radiology department of a university between January of 2019 and January of 2020. Results: A total of 101 patients with DVA were extracted. 38 patients had isolated DVAs, while 63 patients had various accompanying cerebral pathologies, mostly cavernomas (39 patients) and AVMs (11 patients). The main complaints leading investigation were headache, dizziness, ataxia, nausea\vomiting, seizures and focal neurological deficits. 41 patients were truly symptomatic with indicative findings of seizures, neurological deficits or intracranial hemorrhages, and 12 of them had solitary DVAs. 22 patients presented with hemorrhages, and of them, 10 had only DVA, while the rest had some associated lesions, most often cavernoma. Of 22 patients with hemorrhage, 5 were operated, 5 were applied radiosurgery; while the rest were followed without any intervention. Conclusion: Although the symptoms in patients with DVA are generally charged on other associated pathologies, the fact that isolated DVAs may occasionally be problematic in the range of minor symptoms and severe hemorrhage should not be underestimated.
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    Multiple Spinal Meningiomas: A Case Report of a Rare Entity
    (Gazi Univ, Fac Med, 2021) Unal, Mazhar Mufit; Aslan, Ayfer
    The occurrence of multiple meningiomas (MMs) in the spinal canal is a rare clinical entity, if neurofibromatosis is absent. Only 17 cases of multiple spinal meningiomas can be found through a search on the database of pubmed. Moreover, MMs removed from the same patient usually show identical histological features. Considering the rarity of MMs with distinct histological features in the spinal compartment, we described an unusual case with two different subtypes of spinal meningiomas at entirely different levels at the same time and briefly reviewed the related literature.A 47-year-old woman presented with pain, numbness and weakness on the left arm and leg leading to the diagnosis of two intradural extramedullary spinal tumors located anterior to the spinal cord at the levels of C7 - Th2 and Th12 - L1 through magnetic resonance imaging. After successfully removal of both tumors, the histopathological examination revealed meningothelial and psammomatous meningiomas, respectively. Although multiple meningiomas in the spinal compartment is fairly uncommon, this entity should be kept in mind and we suggest screening of other regions of the spine in cases of spinal meningioma, even if without signs of neurofibromatosis.