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Öğe A study on distribution of cancer cases diagnosed in Çorum(Federation of Turkish Pathology Societies, 2014) Baş, Yılmaz; Uzbay, Pınar; Güney, Güven; Erenler, Behice Hande; Yılmaz, Dilek; Özdemir, ÇiğdemObjective: In order to help obtain accurate knowledge and to contribute to the establishment of data for regional tumor statistics, we aimed to determine the frequency distribution of cancer cases that was diagnosed in Çorum province. Material and Method: In this descriptive study, we retrospectively reviewed the archive records of the pathology departments' of one university hospital and two private hospitals serving in the province of Çorum. A total of 138,973 recorded pathology reports were reviewed. Metastatic cancers with a known primary source were excluded. A total of 2184 cases with a diagnosis of cancer were recorded by gender, age, and system/organ and classified to 10 most frequent types of cancer both in general and in terms of gender distribution. Results: The male to female ratio was 1.44 and the mean age was 64.26 years. The cancer is most commonly encountered between 70 and 79 years of age (35.27%) in males whereas the second most common interval was 60 to 69 years of age (23.88%). In females, the cancer is most commonly encountered between 70 and 79 years of age (24.16%) whereas the second most common interval was 60 to 69 years of age (22.60%). The top five cancers were skin (33.60%), prostate (13.87%), stomach (9.07%), urinary bladder (8.61%) and breast (7.88%). Conclusion: Distribution of organ/system involvement of cancer cases that were diagnosed in Çorum is quite different from the data regarding Turkey in general. Development of cancer registry centers, upgrading to an active registry system and having all cancer data from health institutions unified in a single organization are mandatory to achieve reliable data.Öğe Destructive fibrosarcoma of the maxillary sinus(2018) Ekinci, Adnan; Karataş, Duran; Yetiş, Abdurrahman; Erenler, Behice Hande; Özcan, MügeParanasal fibrosarcoma of nasal cavity and paranasal sinuses is a very rare malignant tumor. It is usually presented with nasal obstruction and epistaxis. In this clinical report, clinical symptoms, pathogenesis, and treatment principles of a paranasal fibrosarcoma originating from the right maxillary sinus and obstructing the right nasal passage are discussed.A 55-year-old male patient was admitted to the authors clinic with complaints of nasal obstruction and epistaxis lasting for 2 years. Anterior rhinoscopy revealed a mass lesion which obstructed the right nasal passage and caused frequent epistaxis. An opacity consistent with soft tissue lesion which was originated from the right maxillary sinus and filled the right nasal passage was observed in paranasal tomography. Magnetic resonance imaging revealed that the mass lesion was contrasted. Tumor was seen to erode orbital floor, and lateral and anterior walls of the maxillary sinus. Biopsy result was reported as papilloma. The patient was treated with Denker approach as anterior wall of the maxillary sinus was eroded by the tumor lesion and the mass lesion was excised. The patient received postoperative radiotherapy as pathological diagnosis was reported as paranasal fibrosarcoma.Öğe Distribution of cancer cases between January 01, 2014 and December 30, 2016 in Çorum city, Turkey(Türk Radyasyon Onkolojisi Derneği, 2017) Baş, Yılmaz; Erenler, Behice Hande; Güney, Güven; Turgal, Ebru; Keser, Havva Hande; Şahin, Şahatayi; Tunus, İbrahimOBJECTIVE This study aimed to investigate the frequency and distribution of adult cancer cases in Çorum city, Turkey. METHODS We retrospectively reviewed archive records and found 2204 cancer cases between January 01, 2014 and December 30, 2016 from the records of X University, Faculty of Medicine, Department of Pathology and City Public Health Directorate Cancer Department. RESULTS The mean age of the patients was 65.5 years. The male to female ratio was 1.40, and 41.7% (n=919) of the patients were females and 58.3% (n=1285) were males. The youngest patient was 18 years old and the oldest was 96 years old. The top ten cancers were skin (n=374, 17.0%), lung (n=205, 9.3%), colorectal (n=204, 9.3%), breast (n=192, 8.7%), prostate (n=174, 7.9%), stomach (n=173, 7.3%), urinary bladder (n=159, 7.2%), thyroid (n=136, 6.2%), uncertain primary (n=85, 3.9%), and pancreatic (n=82, 3.7%) cancers. CONCLUSION Development of cancer registry centers, upgrading to an active registry system, and obtaining all cancer data from health institutions and unifying it in a single organization are mandatory to achieve reliable data. Dissemination of screening methods is also important. As a result, determination of local cancer risk factors with the development of early diagnostic methods and the creation of cancer registration system will form the basis for future studies to be developed to prevent cancer.Öğe Hitit Üniversitesi Eğitim ve Araştırma Hastanesi patoloji bölümünde tanısı konulan kanser olgularının dağılımı üzerine bir çalışma(Türkiye Klinikleri, 2015) Baş, Yılmaz; Keser, Havva Hande; Erenler, Behice Hande; Güney, Güven; Yılmaz, Dilek; Ateş, Deniz; Uzbay, PınarObjective: In this study, we aimed to investigate the frequency and distribution of cancer cases evaluating in the province in a certain time period, the number by age and gender, with university hospital pathology laboratory data at our city in Çorum. Material and Methods: Total of 372 cancer cases were diagnosed in our department between 01.05.2013-01.08.2014 at Hitit University, Education and Research Hospital. Types of cancer, the age and sex data were obtained from pathology reports and hospital records system. If necessary, patients and/or to communicate by phone with relatives. Results: 40.03% of patients were female (n=317), 59.97% were male (n=475). The youngest of the patients was 17 and the oldest was 92 years old. Average age was 65,01. According to the organ skin (n=160, 20.20%), prostate (n=90, 11.36%), colorectal (n=86, 10.86%), bladder (n=86, 10.86%), stomach (n=71, 8.98%), thyroid (n=59, 7.45%), breast (n=53, 6.69%), lung (n=32, 4.04%), uterine corpus (n=28, 3.53%), and oral cavity (n=24, 3.03%) cancers were the top ten most common cancers. Women most common skin (n=74, 22.70%), breast (n=53, 16.26%), thyroid (n=47, 14.42%), colorectal (n=34, 10.53%) and uterine corpus (n=28, %8.59) cancers for men prostate (n=90, 19.31%), skin (n=86, 18.45%), bladder (n=78, 16.74%), colorectal (n=52, 11.16%) and stomach (n=19, 10.94%) took the top five cancers. Conclusion: In this study, the skin in men, cancer of the urinary tract and gastrointestinal tract, skin, women, breast and thyroid cancers are the most common cancers. Making serious and extensive research on the etiology is required. The average life expectancy in the incidence of cancer in old age with an increase in elongation is observed. World and Turkey in our region with lung cancer, the most common reasons for non-compliance in general it is necessary to focus on the incidence of common cancers. Cervical cancer is not detected in this study. Screening methods may cause the spread of priority. As a result, the determination of local cancer risk factors with the development of early diagnostic methods, the creation of cancer registration system will form the basis for the project will be developed for the prevention of cancer. © 2015 by Türkiye Klinikleri.Öğe Langerhans cell histiocytosis: diagnosis on thyroid aspirate and effective treatment with systemic chemotherapy(Kuwait Medical Assoc, 2021) Koseoglu, Derya; Erenler, Behice Hande; Kucukler, Ferit KerimLangerhans cell histiocytosis (LCH) is a disease with monoclonal proliferation and infiltration of organs by Langerhans cells. LCH is commonly seen in the skeletal system and skin, but it may also involve parenchymal organs. Thyroid involvement in LCH is an unusual presentation. The treatment of LCH of the thyroid remains unclear because of insufficient data. Here, we present a patient with LCH who had thyroid involvement. She had a lesion in the thyroid, which was detected coincidentally. The diagnosis was made by thyroid aspiration. The patient was treated with systemic chemotherapy and after therapy, the lesion disappeared completely and the patient became euthyroid.