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Öğe A Bibliometric analysis of publications on Spinal Cord injury during 1980–2018(Elsevier Inc., 2020) Kiraz, Murat; Demir, EmreBackground: Spinal cord injury (SCI) could cause motor, sensory loss, severe functional insufficiency, and social problems. This study aims to provide a holistic summary of the global scientific outputs about SCI through bibliometric analyses and reveal the trend topics. Methods: All publications about SCI published between 1980 and 2018 in Web of Science (WoS) index were downloaded (Access date: 01.09.2019) and analyzed using bibliometric methods. In the Title search section in WoS, the documents with the words “spinal cord injury” were identified. Correlation analysis between SCI publication productivity and economic development indicators of the world countries were analyzed using the Spearman correlation coefficient. Results: There were 20,322 publications, 13,662 of which were articles. The top 3 productive countries were the USA, China, and Canada. British Columbia (403; 2.9%), Toronto (401; 2.9%), and Miami (387; 2.8%) were the prominent cities. The top productive journals were Spinal Cord (1,399; 10.24%), Archives of Physical Medicine and Rehabilitation (835; 6.11%), and Journal of Neurotrauma (631; 4.61%). A statistically significant, high-level correlation was found between the number of publications about SCI and the countries' gross domestic product and gross domestic product per capita (r = 0.711, P < 0.001; r = 0.699, P < 0.001). Conclusions: This study provides a systematic analysis of SCI and could be a beneficial guide for clinicians and scientists.Öğe A Holistic Investigation of Global Outputs of Covid-19 Publications in Neurology and Neurosurgery(2020) Kiraz, MuratObjectives: Neurological and neurosurgical management of the global COVID-19 crisis could only be possible by extending the current literature and rapidly delivering this current data to clinicians. The purpose of this study is to analyze the global outputs of COVID-19 in the field of neuroscience through bibliometric methods and provide a guide to researchers who would like to contribute to the literature by conducting research in this field. Methods: Bibliometric analysis was performed for all the publications in Web of Science database in Neurosciences Neurology (Clinical Neurology, Neurosciences, Neuroimaging) research areas and included the “COVID-19”, “coronavirus”, “2019-nCoV”, “n-CoV”, and “SARS-CoV-2” keywords in their title. Results: The literature review included 13785 publications in all research areas. Of these publications, 459 were published in the field of Neurosciences Neurology. The top 5 countries that produced the highest number of publications were the USA (139, 30.2%), Italy (110, 23.9%), UK (57, 12.2%), China (49, 10.6%), and Germany (43, 9.3%). The journals that produced the highest number of publications were Brain Behavior and Immunity, Journal of Neurology, Neurological Sciences, Nature Human Behavior and Acta Neurochirurgica. The most commonly investigated topics were stroke, encephalitis, depression, mental health, stress, neurosurgery, Parkinson’s disease, Guillain-Barre syndrome, multiple sclerosis, anxiety, and headache. Conclusion: The present study has the potential to provide a guide that can contribute to the improvement in the literature.Öğe An international bibliometric study of scientific articles on intracranial aneurysms(Sage Publications Inc, 2021) Kiraz, Murat; Demir, Emre; Özdemir, ÖmerObjectives: The number of original scientific researches on intracranial aneurysms has risen over the last 30 years. Despite the rise in the number of articles, there is no up-to-date exhaustive bibliometric research in the literature. This study aimed to contribute to the literature via a bibliometric analysis of the original scientific researches on intracranial aneurysms published over the last 30 years. Methods: The literature review was done using the Web of Science. All articles and its citations containing aneurysm keywords were analyzed in the title section of articles published in the research areas: Neurosciences Neurology during 1980-2019. Correlation analyses between the number of articles produced by the countries and their economic and development indicators of gross domestic product, and Human Development Index were analyzed using the Spearman correlation coefficient. Linear regression analysis was utilized to estimate the number of articles to be published in the future. Results: There were a total of 21,673 publications on intracranial aneurysms. Of these publications, 13,371 (61.7%) were articles. The three countries that produced the most articles were the USA (4098), Japan (2668), and China (937). A statistically significant correlation was found between the development indicators of world countries and publication productivity (p<0.001). The three journals that produced the most publications were Neurosurgery, Journal of Neurosurgery, and American Journal of Neuroradiology. The most cited article was published in Journal of Neurosurgery. Conclusion: This bibliometric study provides a collection of data that will help design future research on intracranial aneurysms more efficiently and make innovations at greater speed.Öğe An Investigation of the Effect of Anxiety and Religious Beliefs on Decision-Making Attitudes to Lumbar Microdiscectomy(Discovery Publication, 2020) Kiraz, Murat; Kiraz, SedaBackground: The effects of religious beliefs on health have been investigated for many years. Although this issue has been investigated in many scientific studies, whether there is a significant relationship between anxiety and religiousness is still discussed. This study aims to investigate the effects of anxiety levels and religiousness on Lumbar Microdiscectomy acceptance attitudes. Methodology: The participants were divided into two groups as those who accepted Lumbar Microdiscectomy and those who did not; these patients were asked to fill in two different forms that were developed to measure pre-operative anxiety level and religiousness level. The patients' religiousness level was identified using the Religious Orientation Scale. The anxiety levels of the patients were determined by using Anxiety Specific to Surgery Questionnaire. Results: The anxiety level of the group that did not accept an operation was 33.48 +/- 8.05, which was significantly higher than the anxiety level (27.12 +/- 7.32) of the group which accepted an operation (p=0.001). The Pearson correlation analysis performed between the anxiety and religiousness scale scores indicated a significant, weak-level, and negative relationship (p=0.033, r=-0,320). When the effect of anxiety level between the groups who accepted an operation and who did not is controlled with ANCOVA test, no significant differences were found between the religious scale scores of the groups (p=0.572). Conclusion: Apart from the effect of religiousness, decision for Lumbar Microdiscectomy is considered to be affected by several multidimensional factors such as patients' anxiety levels, previous disease experiences, importance they give to quality of life, post-operative risks such as experiencing severe pain or getting paralyzed, anxiety of leaving from the family, loss of independence, fear of operation, and fear of death.Öğe Cortical and Subcortical Brain Volume Alterations Following Endurance Running at 38.6 km and 119.2 km in Male Athletes(Int Scientific Information, Inc, 2021) Singin, Rabia Hurrem Ozdurak; Duz, Serkan; Kiraz, MuratBackground: Although several studies have shown that ultramarathon running causes severe physical and mental stress and harms organ systems, its effect on brain tissue remains unclear. The purpose of this study was to investigate the volumetric change of cortical and subcortical brain structures following 38.6-km and 119.8-km mountain races. Material/Methods: A total of 23 healthy male runners (age, 49.05 +/- 5.99 years) were classified as short-trail (ST; n=9) and ultra-trail (UT; n=14) endurance running. Pre- and post-test scanning of brain tissue was performed by using a 3-Tesla magnetic resonance imaging (MRI). Pre- and post-race differences in cortical and subcortical volumes in the ST and UT groups were separately determined by Wilcoxon signed-rank test. Results: Cortical gray matter (GM) and cerebral GM volume significantly increased after the race in both ST and UT groups, whereas the volume of the thalamus, caudate, pallidus, and hippocampus significantly increased only in the UT group. Cerebrospinal fluid (CSF) and white-matter (WM) volumes did not change after endurance running and remained unaltered in both groups. Conclusions: Endurance running has a site-specific acute effect on cortical and subcortical structures and may attenuate GM volume decrease in older adult male athletes. The increased volume of subcortical structures might be a response of physical exercise and additional physical stress experienced by ultramarathon runners.Öğe Mitochondrial Membrane Protein-Associated Neurodegeneration as The Cause of Psychosis(Turkish Assoc Psychopharmacology, 2020) Kiraz, Seda; Kiraz, MuratHallucinations and delusions can be an initial symptom of many medical conditions as well as psychiatric disorders. These medical conditions can be endocrinological, immunological, neurological or genetic diseases. NBIA (Neurodegeneration with Brain Iron Accumulation) is a very rare genetically inherited mixed disorder that can occur with neurological, psychiatric or neuropsychiatric symptoms. MPAN (Mitochondrial Membrane Protein-Associated Neurodegeneration) is a recently described NBIA subtype. In this article, MPAN case with visual hallucinations and cognitive destruction was discussed. Also, we aimed to present the clinical features of MPAN and to underline the importance of the physical and neurological examination and the combination of findings with appropriate tests in the process of diagnosis.Öğe Nanoteknoloji ve Nanonöroşirürji(2018) Kiraz, Murat; Çevik, Serdar; Demirel, Altan; Gergin, Yusuf Emrah; Özdemir, ÖmerNanoteknoloji atomların farklı dizilişleriyle; üretim tekniklerinde yenilik yapmak ve ihtiyaca uygun üstün özellikli yeni ürünler geliştirmektir. Nanonöroşirürji ise nanoteknoloji ile kombine hücresel ve moleküler biyoloji kullanılarak, merkezi ve periferik sinir sisteminin, hücre ve mikrohücre düzeyinde nano ölçekli manipülasyonu olarak tanımlanır. Nanoteknoloji, mevcut görüntüleme modalitelerinin çözünürlüğünün ve duyarlılığının artırılmasında, beyin tümörlerinin tedavi planlamasında, özellikle de glioblastoma gibi malign neoplazmlar ile ilgili mevcut yaklaşımın değiştirilmesinde, omurga hastalıklarının tedavisinde yeni yapısal destek ve enfeksiyon oranlarının azaltılmasını amaçlayarak gelişmeye devam etmektedir. Ayrıca nöral doku mühendisliği açısından, nano malzemeler nörorejenerasyon sürecini yönlendirebilecek niteliktedir. Nanoteknoloji, hücresel ve moleküler düzeye müdahaleyi kolaylaştırarak nöroşirürjiyi değiştirme gücüne sahiptir. Bu derleme yazısında, gelişmekte olan nanoteknoloji tekniklerinin nöroşirürji ile ilgili potansiyel önemi değerlendirildi.Öğe Relationship of lumbar disc degeneration with hemoglobin value and smoking(Masson Editeur, 2020) Kiraz, Murat; Demir, EmreBackground/objectiveAlthough a number of studies report an important effect of smoking on disc degeneration and herniation, others did not identify such a relationship. The purpose of this study was to assess the relationship of lumbar disc degeneration with hemoglobin value and smoking.Methods The study included 200 adult patients who presented to the neurosurgery polyclinic with a complaint of back pain. Smoking habits were classified as “smoking for more than 10 years”, “smoking for less than 10 years”, and “not smoking”. Lumbar disc degeneration was classified on modified Pfirrmann score according to lumbar MR images. Degeneration level was compared according to smoking group on Kruskal-Wallis test. The relationship between hemoglobin value and disc degeneration according to smoking group was assessed on the Spearman correlation coefficient. ResultsDisc degeneration values were significantly different between groups in L5-S1, L4-L5 and L3-L4 (P = 0.018, P = 0.012, P = 0.038). Degeneration levels in L5-S1 in those who did not smoke were significantly lower than in those who smoked for both less and more than 10 years (P = 0.048, P = 0.022). No significant differences were found in degeneration level between those who smoked for more versus less than 10 years. For L3-L4 degeneration, there was a significant relationship with hemoglobin value in the group that did not smoke and in the group that smoked for more than 10 years r = ?0.395; P = 0.009, r = 0.329; P = 0.018).ConclusionThis study found that, when risk factors such as systemic disease, heavy working conditions, obesity, trauma and family history were excluded, smoking increased lumbar disc degeneration. In addition, chronic smoking was found to increase hemoglobin values.
