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Yazar "Mutlu, V" seçeneğine göre listele

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  • [ X ]
    Öğe
    Effects of Bariatric Surgery on Sleep Disorder Symptoms and Sleep Quality
    (SPRINGER, 2025) Mutlu, V; Karacı, R; Yüksek, MA; Şahin, S; Domaç, FM; Özbalcı, GS; Yılmaz, K
    Objectives Obesity is related with several sleep disorders and affects the quality of life. In this research it was aimed to evaluate the effects of bariatric surgery on sleep disorders and sleep quality. Methods The study was conducted on 454 patients who underwent bariatric surgery at the Departments of General Surgery of & Uuml;sk & uuml;dar University, Hitit University, Ondokuz Mayis University, and sleep disorders were evaluated at University of Health Sciences Erenk & ouml;y Mental and Nervous Diseases Training and Research Hospital, Department of Neurology. Sleep quality of the patients, reporting complaints about sleep. was assessed with the Pittsburgh sleep quality index (PSQI), risk of obstructive sleep apnea syndrome was questioned with the Berlin Sleep Questionnaire (BSQ), excessive daytime sleepiness was screened with the Epworth Sleepiness Scale (ESS). The Insomnia Severity Index (ISI) was used in patients who identified insomnia and the restless legs syndrome severity scale (RLSS) index was also evaluated in patients with the complaints of RLS before and after the bariatric surgery. Results Among 454 patients, 207 of them (45.6%) have informed complaints about sleep. After bariatric surgery, all scores indicating impaired sleep quality (BSQ category 1 and category 2, RLS index, ESS, PSQI, ISI) decreased significantly in patients (p = 0.000). BSQ- scale scores had the greatest decrease among other scales. Patients also reported fewer complaints of sweating, sexual dysfunction, gastroosephageal reflux, teeth clenching, dry mouth, morning headache, nocturia, and daytime sleepiness after the surgery (p < 0.05). The decrease in body mass index (BMI) was significantly correlated with BSQ-OSAS total (r=-0.143; p < 0.05), RLS (r=-0.410; p < 0.05) and PSQI sleep latency (r = 0.174; p < 0.05). However, the correlation between BMI reduction and ESS, PSQI and ISI scores was found statistically insignificant. (p > 0.05). Effect of BMI difference on BSQ-OSAS was statistically significant (OR=-0.041; p < 0.05). Effects of BMI difference (OR=-0.490; p < 0.05) and having thyroid comorbidity (OR=-24.752; p < 0.01) on RLS were also statistically significant. Conclusion Bariatric surgery has a positive and healing effect on sleep apnea and restless legs syndrome in favor of this group of patients.
  • [ X ]
    Öğe
    Investigation of the effects of laparoscopic sleeve gastrectomy and laparoscopic one anastomosis gastric bypass on metabolic syndrome components
    (BMC, 2025) Mutlu, V; Yüksek, MA; Koca, B; Özbalcı, GS
    Background Obesity and accompanying comorbidities are serious diseases that impair the quality of life and even threaten human life. Today, the most effective method for providing sustainable weight loss in the treatment of obesity is Bariatric and Metabolic Surgery procedures. In our study, we aimed to compare the therapeutic effects of Laparoscopic Sleeve Gastrectomy (LSG) and One Anastomosis Gastric Bypass (OAGB) on metabolic syndrome components. We also planned to investigate the complications after bariatric and metabolic surgery, whether the patients had recurrent weight gain, and the short, medium and long-term effects. Methods Patients who underwent bariatric and metabolic surgery with the diagnosis of obesity between December 2012-January 2020 were retrospectively analyzed. 561 patients who were followed up at 3, 6 months, 1, 2 and 3 years after the operation were included in the study. The effects of bariatric and metabolic surgery on metabolic syndrome components were evaluated as partial and complete remission according to the status at the last follow-up. Statistical analysis were performed by SPSS 18. Results were reported as mean +/- standard deviation. P < 0.05 was accepted as statistical significance. Results In 516 patients who underwent LSG and 45 patients who underwent OAGB, a decrease in BMI and an increase in EWL(%) values were observed at the 3rd month, 6th month, 1st year and 2nd year controls. In the 3rd year controls of patients who underwent LSG, recurrent weight gain was observed, therefore there was an increase in BMI and a decrease in EWL(%) values compared to the 2nd year. In patients who underwent OAGB, a decrease in BMI continued at the 3rd year, while an increase in EWL(%) values was observed. Thanks to both LSG and OAGB; a remission was achieved at the rates of DM, HT, HL/DL, OSAS, hypothyroidism in the early period. As the follow-up period extended, the rate of patients showing complete recovery decreased for DM(p = 0.0001). No change was observed during the follow-up period for other parameters. Conclus & imath;on Therapeutic effects of LSG and OAGB on metabolic syndrome components have been demonstrated in our study. However, when DM remission and sustainable weight loss are evaluated, OAGB is more effective in the long term.
  • [ X ]
    Öğe
    Radiologist- and Surgeon-Performed Ultrasound (RSUS) Facilitates Minimally İnvasive Parathyroidectomy (MIP): Optimal Biochemical Parameters and Patient Outcomes
    (MDPI, 2025) Mutlu, V; Yüksek, MA; Pekkolay, Z; Yeğin, Z; Yıldırım, İH; Uslukaya, O
    Background/Objectives: The high success rate of minimally invasive parathyroidectomy (MIP) is dependent upon the correct preoperative localization of the solitary parathyroid adenoma (SPA). Various studies have focused on comparisons of radiologist-performed ultrasound (RUS) and surgeon-performed ultrasound (SUS) to increase the sensitivity rate of US. However, the efficiency of radiologist- and surgeon-performed ultrasound (RSUS) before MIP has not frequently been reported. We aimed to evaluate the efficiency of RSUS in clinical practice. Methods: In total, 122 patients (107 females, 15 males, mean age: 47.62 +/- 15.75 years) with SPA were enrolled in our study design. The patients underwent preoperative ultrasonography (US) and technetium-99-sestamibi scintigraphy. Patient data including demographic characteristics, levels of biochemical parameters (parathyroid hormone (PTH), total serum calcium and phosphorus levels), operation time, and length of hospital stay were recorded. Results: MIP was performed with success under local anesthesia following the accurate localization of the adenomas by RSUS. The mean operation time was 20.00 +/- 3.87 min. The mean preoperative serum PTH, calcium, and phosphorus levels were 525.69 +/- 1050.92 pg/mL, 11.38 +/- 1.22 mg/dL, and 2.53 +/- 0.60 mg/dL, respectively. The decline in the perioperative PTH and calcium levels reflecting a cure was observed on the first postoperative day. Postoperative sixth month evaluations of the PTH and calcium levels confirmed the significant decrease, reflecting the therapeutic cure. Since no complications occurred, the hospital discharge process was carried out on the same day. Conclusions: RSUS is a beneficial adjunctive tool to facilitate MIP, and it achieved satisfactory therapeutic success in all the patients.

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