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    Öğe
    Association of ferritin levels with depression, anxiety, sleep quality, and physical functioning in patients with fibromyalgia syndrome: a cross-sectional study
    (NLM (Medline), 2019) Okan, Sevil; Çağlıyan Türk, Ayla; Şıvgın, Hakan; Özsoy, Filiz; Okan, Fatih
    Aim To determine the frequency of ferritin deficiency in individuals with fibromyalgia syndrome (FMS) and to evaluate the association of ferritin level with depression, anxiety, sleep quality, and physical functioning.Methods This cross-sectional study, conducted from 2016 to 2017, compared the frequency of ferritin deficiency between 100 non-anemic fibromyalgia patients and 100 nonanemic individuals without FMS. Serum ferritin level of <30 ng/mL indicated iron deficiency. FMS patients filled out demographic questionnaire, Fibromyalgia Impact Questionnaire, Beck Anxiety Inventory, Beck Depression Inventory, and Pittsburg Sleep Quality Index.Results Median serum ferritin level was 20.95 ng/mL. A total of 64% of patients and 42% of controls had iron deficiency. Beck Anxiety Inventory, Beck Depression Inventory, and Pittsburgh Sleep Quality Index scores were not associated with ferritin levels. FMS patients with poor sleep quality had significantly higher Beck Depression Inventory, Beck Anxiety Inventory, and Fibromyalgia Impact Questionnaire scores (P< 0.05). In individuals with poor sleep quality, lower ferritin levels also correlated with higher Beck Depression Inventory scores (r - -0.277, P< 0.05). Sleep quality was not significantly associated with age, body mass index, duration of diagnosis, and serum ferritin levels Conclusions Patients with fibromyalgia syndrome have a rather high prevalence of non-anemic iron deficiency. No associations were found between serum ferritin level and anxiety, depression, sleep quality, and physical functioning.
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    Öğe
    Bel Ağrılı Genç Erişkinlerde Lomber ve Servikal Manyetik Rezonans Görüntüleme Bulgularının Karşılaştırılması
    (2018) Türk, Ayla Çağlıyan; Okan, Sevil; Fidan, Nurdan; Musmul, Ahmet; Şahin, Füsun
    Amaç: Servikal bölgede ağrısı olmayan bel ağrılı genç erişkinlerin, lomber bölge manyetik rezonans görüntüleme (MRG) bulguları ile servikal bölge MRG bulgularını karşılaştırmak ve bu bulguların risk faktörleriyle ilişkisini saptamaktır. Gereç ve Yöntemler: Çalışmaya yaş aralığı 20-40 yıl olan, bel ağrısı olan, boyun ağrısı olmayan 60 hasta alındı. Bel ağrısının süresi, sigara içimi, travma öyküsü, düzenli egzersiz yapıp yapmadığı, boyu, kilosu ve mesleği sorgulandı. Beden kitle indeksi (BKİ) hesaplandı. Ağrı, vizüel analog skala (VAS) ile değerlendirildi. MRG’de; herniasyon, dejenerasyon ve anüler yırtık kaydedildi. Dejenerasyon derecelendirildi. Bulgular: Hastaların ortalama yaşı 29,82±5,59 yıl, BKİ 25,36±3,82 kg/m2 , bel ağrısı süresi 32,02±29,97 ay, bel ağrısı VAS 6,83±1,45 idi. Herniasyon lomber bölgede en fazla L4-5 ve L5-S1 düzeyinde olup; bulging (%45- 36,7), protrüzyon (%41,7-51,7), ekstrüzyon (%8,3-6,7) şeklinde dağılım gösterirken, servikal bölgede ise en fazla C5-6 ve C4-5 seviyesinde olup; bulging (%51,7-30) ve protrüzyon (%13,3-11,7) şeklinde dağılım gösterdi. Lomber bölgede 188 (%52,2) seviye normal, 172 (%47,7) seviyede disk hernisi bulgusu, servikalde ise 234 (%65) seviye normal, 126 (%35) seviyede disk hernisi bulgusu mevcuttu. Dejenerasyon en fazla L5-S1, L4-5 ile C3-C4, C4-5 seviyelerindeydi. Lomber bölgede Gr8’e, servikalde Gr5’e ulaşan dejenerasyon saptandı. Lomber disk hernisi (r=0,303) ve dejenerasyonu (r=0,398) kilo ile servikal bölge disk hernisi (r=0,279) ve disk dejenerasyonu (r=0,273) yaş ile pozitif ilişkili idi. Lomber ve servikal bölge herni ve dejenerasyon skorları arasında korelasyon yoktu. Sonuç: Servikal ağrı şikâyeti olmayan genç erişkinlerde de pozitif MRG bulguları olabilmektedir. Omurganın farklı bölümleri risk faktörlerinden farklı etkilenebilmektedir. Yaş ve BKİ omurga sağlığını etkileyen risk faktörleri arasında sayılabilmektedir.
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    Öğe
    Comparing the efficiency of ultrasound, ketoprofen, and mucopolysaccharide polysulfate phonophoresis in the treatment of lateral epicondylitis: A randomized-controlled clinical study
    (2020) Okan, Sevil; Türk, Ayla Çağlıyan
    Objectives: In this study, we aimed to compare the efficiency of ultrasound, mucopolysaccharide polysulfate phonophoresis, ketoprofen phonophoresis and exercise combinations in terms of pain, functionality, disability, and strength in patients with lateral epicondylitis (LE). Patients and methods: This prospective, parallel-group, randomized-controlled clinical study included a total of 60 patients (42 males, 18 females; mean age 38.08 years; range, 21 to 50 years) with LE between April 2016 and October 2017. The patients were equally randomized into four groups based on the time of admission to the outpatient clinic. The Visual Analog Scale (VAS), painless weight lifting, the Patient?Rated Tennis Elbow Evaluation (PRTEE), and Quick Disabilities of Arm, Shoulder and Hand (QuickDASH) were used to measure the outcomes. The measurements were performed at baseline, at the end of 10 daily sessions, and after a six-week follow-up period. Results: The resting VAS scores in the ketoprofen phonophoresis group and lifted weights in the MPS and ketoprofen phonophoresis groups showed a significant improvement both after 10 days of treatment and at six-week follow-up visits (p<0.001). In the QuickDASH model, there was no significant improvement in the control group after 10 days of treatment (p>0.05); however, a significant improvement was observed after six weeks (p<0.001). Except for these variables, significant improvements were found in all groups for all variables at six-week follow-up (p<0.05). However, improvements were similar in all groups (p>0.05). Conclusion: Based on our study results, for LE patients who are unable to adhere to exercise and splint use and are given a physical treatment plan, inclusion of ketoprofen and MPS phonophoresis in the treatment program may yield additional benefits in their daily living activities, functionality, and working life.
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    Öğe
    The Frequency Of Fibromyalgia In Female Patients With Impaired Fasting Blood Glucose: Crosssectional Study
    (2020) Türk, Ayla Çağlıyan; Okan, Sevil; Özel, Sumru; Musmul, Ahmet; Bağlıcakoğlu, Murat; Küçükler, Ferit Kerim; Şahin, Füsun
    Objectives: To assess the frequency of fibromyalgia among women with impaired fasting glucose. Materials and Methods: The sample was selected from the female patients who applied to the Internal Medicine clinic and whose fasting blood glucose level were 100-126 in their routine examination (Group1) and patients whose fasting blood glucose were less than 100 constituted the control group (Group2). Oral glucose tolerance test (OGTT) has been applied to patients with impaired fasting glucose (IFG) and whose 2nd hour OGTT levels were under 140 has been included. Functional status was assessed by using the Fibromyalgia Impact Questionnaire (FIQ). Pain Location Inventory (PLI), and Symptom Impact Questionnaire (SIQR) were evaluated for the diagnosis of fibromyalgia. Results: Mean age was 48.99±7.50 in Group1 (n=73) and 47.84±7.92 in Group2 (n=73) with no significant difference between them. Mean BMI (body mass index) was 30.41±5.01 in Group1 and 28.00±4.61in Group2, this difference was significant (p<0.05). 26% of the patients in Group1, 11% of the patients in Group2 were diagnosed with fibromyalgia and difference was highly significant (p<0.001). Mean FIQ was 44.27±21.98 in Group1 and 24.95±21.49 in Group2, this difference was also significant (p<0.001). Glucose level was associated with PLI (r=0.368, p<0.001), SIQR (r=0.322 p<0.001) and FIQ (r= 0.287, p<0.001). Conclusion: Fibromyalgia is more prevalent in female patients with IFG than in patients with normal fasting glucose levels. Glucose level is associated with both PLI, SIQR and functionality. Although not a clinical disease, IFG is not only a risk factor for development of diabetes but also a risk factor for fibromyalgia in women.