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Yazar "Sahin, Tayfun" seçeneğine göre listele

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  • [ X ]
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    Anterior chamber changes assessment by Scheimpflug analysis after intravitreal dexamethasone implantation
    (Sage Publications Ltd, 2021) Kucukkomurcu, Elvan; Sahin, Tayfun
    Purpose: To evaluate structural changes in the anterior chamber and intraocular pressure (IOP) changes following intravitreal dexamethasone implantation. Methods: Forty-two eyes of 42 patients that received intravitreal dexamethasone implant for the management of macular edema secondary to diabetic retinopathy or branch retinal vein occlusion (BRVO) were included in the study. IOP was measured by Goldmann applanation tonometry. Anterior chamber depth (ACD) and iridocorneal angle (ICA) was measured by a Scheimflug camera (Sirius, CSO, Italy) the day before the injection of the dexamethasone implant and on postoperative day 1, first week, and first month. Results: Mean IOP was 15.14 +/- 2.77 mmHg before the procedure and, 15.67 +/- 3.70 mmHg, 15.86 +/- 3.11 mmHg, 16.21 +/- 2.75 mmHg on day 1, first week, and first month following intravitreal dexamethasone implantation, respectively. Mean ICA and ACD were significantly higher in pseudophakic eyes compared to phakic eyes. However, there was no statistically significant change in ICA before and after the procedure (on postoperative day 1, first week, and first month) among both phakic and pseudophakic patients (p = 0.783). Similarly, ACD remained unchanged after the procedure (on postoperative day 1, first week, and first month) compared to the initial measurement (p = 0.802). Conclusion: This study confirmed that there was an increase in IOP. However, these changes were not accompanied with a change in ACD or ICA.
  • [ X ]
    Öğe
    Does anisometropia affect the ciliary muscle thickness? An ultrasound biomicroscopy study
    (Springer, 2020) Cevher, Selim; Sahin, Tayfun
    Purpose To compare the ciliary muscle thickness (CMT) of the normal fellow eye to that of the amblyopic eye using ultrasound biomicroscopy (UBM) in patients with unilateral anisometropic amblyopia. Methods Thirty patients with unilateral anisometropic amblyopia were involved. The patients were divided into two groups: 19 hyperopic and 11 myopic. Axial length (AL) was measured with optic biometry and anterior chamber depth (ACD), iris area, and CMT were measured with UBM. Results The mean age was 34.10 +/- 6.61 years. The mean spherical difference between two eyes was 2.59 diopter (D) in hyperopic patients and 3.77D in myopic patients. In the hyperopic patients, nasal CMT1(nCMT), temporal CMT1(tCMT), tCMT2, and tCMT3 values were statistically thinner in amblyopic eyes than healthy eyes (p = 0.036,p = 0.003,p = 0.023,p = 0.005, respectively). ACD values were statistically lower in amblyopic eyes (2.78 +/- 0.26 mm) than healthy eyes (2.90 +/- 0.21 mm) (p < 0.001). In the myopic patients, nCMT1, nCMT2, nCMT3, tCMT1, tCMT2, and tCMT3 values were statistically thicker in amblyopic eyes than healthy eyes (p = 0.003,p = 0.003,p = 0.005,p = 0.003,p = 0.003,p = 0.019, respectively). ACD values were statistically higher in amblyopic eyes (3.20 +/- 0.30 mm) than healthy eyes (3.06 +/- 0.29 mm) (p = 0.004). Also, there was no significant difference in the iris area between the amblyopic and normal eyes of the myopic and hyperopic patients (p > 0.05). Conclusions Amblyopic eyes in patients with unilateral myopic anisometropia have thicker CMT and deeper ACD than healthy eyes. Conversely, amblyopic eyes in patients with unilateral hyperopic anisometropia have thinner CMT and shorter ACD than healthy eyes. There is a positive correlation between AL and CMT.
  • [ X ]
    Öğe
    Does Rosacea, a localized skin disease, affect the choroidal thickness?
    (Wiley, 2021) Sahin, Tayfun; Oztekin, Aynure; Cevher, Selim
    Introduction This study aims to compare the choroidal thickness (CT) of patients with rosacea with healthy individuals. Methods This study was conducted with 42 patients with Papulopustular Rosacea (PPR), 38 patients with Erythematotelangiectatic Rosacea (ETR), and gender and age-matched 37 healthy individuals in the control group. CT measurements were done using the spectral-domain optical coherence tomography. Results Choroidal thickness means were measured as 352 +/- 78 mu m, 331 +/- 67 mu m, and 346 +/- 83 mu m at the subfoveal region; 323 +/- 72.3 mu m, 303.5 +/- 68.4 mu m, and 314 +/- 80.3 mu m at 1000 mu m nasal; and 325.2 +/- 71 mu m, 304.4 +/- 52.2 mu m, and 309 +/- 67 mu m at 1000 mu m temporal in the PPR, ETR, and control groups, respectively (p > 0.05). Conclusion Although rosacea is a common chronic skin disease that could have systemic findings, CT is not affected by this disease.
  • [ X ]
    Öğe
    Retinal Nerve Fiber Layer Thickness in Opioid Abusers
    (Turkish Assoc Psychopharmacology, 2020) Karadere, M. Mehmet; Sahin, Tayfun; Cobanoglu, Ebru; Yildiz, Veysi
    Background: Opioids are addictive substances that have been shown to have neurotoxic effects on the brain. These neurotoxic effects may be associated with retinal nerve fiber layer (RNFL) thickness. This study aims to examine retinal neural fiber layer thickness by optical coherence tomography (OCT) among opioid addicts. Methods: Therefore, both eyes of the 45 participants who met the diagnosis of opioid addiction according to DSM-5 (age:26.13 +/- 6.20 years) and 45 healthy control groups (age:28.87 +/- 9.04 years) were examined in seven quadrants (superior temporal, superior nasal, temporal, nasal, inferior temporal, inferior nasal quadrants and global RNFL thickness) with OCT. Results: Mean RNFL thicknesses in any quadrant did not differ statistically significantly between the groups (p>0.05). Furthermore, there was no statistically significant correlation between the duration of substance use and RNFL thicknesses. There is a statistically significant inverse correlation that has been found between the daily amount of substance use (gr) and RNFL thicknesses in the right eye temporal inferior (r: - 0,499) and temporal superior (r: - 0,351) and left eye nasal inferior (r: - 0,387) quadrants, whereas there was not any statistically significant correlation in other quadrants. Conclusions: This study suggests that RNFL thickness may be the same as healthy controls for several reasons in opioid addicts. It would be appropriate for this to be confirmed by broader studies and for its mechanism to be investigated.

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