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Öğe Comparative Effect of Feeding Human Milk as Opposed to Formula on Visual Function and Ocular Anatomy(Mary Ann Liebert, Inc, 2019) Bozkurt, Erdinc; Bozkurt, Hayrunnisa Bekis; Ucer, Mehmet BarisBackground/Objective: Performance of ocular examinations on children who were breastfed, fed with formula, and combination of the two for the first 6 months of age. Subsequently, refractive errors, allergic conjunctivitis, and retinal nerve fiber layer (RNFL) thickness were evaluated. Materials and Methods: The present study included a total of 242 eyes of 121 children (aged 60-84 months, 65 males, 56 females) admitted to the outpatient clinic of our institution. The patients were divided into three groups according to their feeding pattern during their first 6 months postdelivery: breastfed children (Group 1, n = 40), children fed with a combination of breast and formula milk (Group 2, n = 41), and children exclusively fed with formula-milk (Group 3, n = 40). All patients underwent detailed ophthalmologic examinations, and measurements of the RNFLs were recorded. Results: No significant difference was observed between the groups in terms of refractive error. In Group 3, we found that allergic conjunctivitis was significantly higher than in the other groups. In addition, in Group 3, the thickness of the RNFL was found to be significantly higher in the superior quadrants of both the eyes of children than in Groups 1 and 2 (p < 0.05). Conclusions: We found that the type of feeding experienced by infants in their first 6 months has no effect on refractive error but has significant effects on both allergic conjunctivitis and RNFL. To determine the cause of this difference in the RNFL and to further validate the present study, future studies with larger patient groups and animal experiments are needed.Öğe Comparison of central corneal thickness measurements with three different optical devices(Sage Publications Ltd, 2021) Ucer, Mehmet Baris; Bozkurt, ErdincPurpose: The purpose of this study was to compare and evaluate the agreement of central corneal thickness (CCT) values obtained with three different devices working according to optical principle in healthy eyes. Methods: 60 eyes of 60 individuals (30 men and 30 women) were enrolled in this study. CCT measurements performed with Scheimpflug-Placido topographer (Sirius), spectral-domain optical coherence tomography (RTVue) with an anterior segment module, and optical biometer (AL-Scan) were compared. Bland-Altman analysis was used to demonstrate agreement between methods. Results: The mean age was 30.07 +/- 7.313 years (range, 18-47 years). The mean CCT values obtained by RTVue, Sirius, and AL-Scan were 518.25 +/- 36.38 mu m, 526.08 +/- 36.33 mu m, and 513.50 +/- 39.09 mu m, respectively. The mean differences in CCT were 7.83 +/- 14.15 mu m between Sirius and RTVue, 12.58 +/- 11.87 mu m between Sirius and AL-Scan, and 4.75 +/- 4.50 mu m between RTVue and AL-Scan. The mean CCT was statistically different among the three groups (p <0.05). All three modalities of CCT measurements correlated closely with each other, with Pearson's correlation coefficients ranging from 0.924 to 0.961. The 95% limits of agreement were -19.90 to 35.56 mu m between Sirius and RTVue, -10.69 to 35.85 pm between Sirius and AL-Scan, and -4.07 to 13.58 mu m between RTVue and AL-Scan. Conclusion: Different results could be obtained through different noncontact devices in CCT measurements. Although the measurement values obtained by these devices show a high level of correlation, it would be a more correct approach to not use them directly interchangeably in clinical practice. Evaluation and follow-up of CCT should be performed using the same device.Öğe Isolated foveal hypoplasia without nystagmus: Imaging findings(Bayrakol Medical Publisher, 2019) Ucer, Mehmet Baris; Bozkurt, ErdincFoveal hypoplasia (FH) is commonly associated with other ocular anomalies as well as rarely as isolated. In this study, we reported the clinical features and imaging findings of an isolated FH without nystagmus. A 24-year-old female referred to the outpatient clinic complaining on non-progressive, mild visual impairment since early childhood without nystagmus. Spectral domain-optical coherence tomography (SD-OCT) revealed the absence of fovea; depression in both eyes with continuity of all inner retinal layers. No capillary-free zone was observed in fluorescein angiography. In suspected cases, SD-OCT is a quick and non-invasive method for diagnosis but other imaging modalities may also helpful.Öğe Observation of the development and spontaneous closure of a traumatic macular hole by optical coherence tomography(Bayrakol Medical Publisher, 2019) Ucer, Mehmet Baris; Soysal, Hulya Gokmen; Coban, Mehmet Sait; Kalayci, DefneWe report a case of a traumatic macular hole (TMH) formation which occurred several days after a blunt trauma in a child in order to demonstrate its spontaneous closure by daily optical coherence tomography (OCT) findings. A nine-year-old boy applied to the outpatient clinic with skin injury in the zygoma region which was caused by blunt trauma. Foveal contour was normal and subretinal and intraretinal fluid was detected on OCT. On the 2nd day, the subretinal fluid increased. On the 3rd day, there was a slight separation between the outer plexiform layer and the outer nuclear layer, suggesting a lamellar hole. A full-thickness macular hole with a base width of 360 microns was observed on the 7th day. On the 3rd week of follow-up, the OCT revealed closure of macular hole. A slight foveal depression and highly reflective accumulation and shadowing of retinal pigment epithelium were detected. A spontaneous closure may be observed in TMHs, especially in patients within the pediatric age group. Observation may be a better therapeutic option for TMHs before deciding on a macular surgery in childhood.