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Öğe Can platelets be the early biomarkers of erectile dysfunction?(Pakistan Medical Association, 2018) Şentürk, Aykut Buğra; Yaytokgil, Muhammet; Yılmaz, Ali Haydar; Ekici, Musa; Aydın, Cemil; Demir, Emre; Çakıroğlu, BasriObjective: To assess the relationship between erectile dysfunction and platelet count and other platelet indices. Methods: The case-control study was done at Hitit University Erol Olcok Training and Research Hospital, Turkey, and comprised patient data between January 2014 and September 2016 that was compared with age-matched controls with no history of erectile dysfunction who were randomly chosen from patients attending the urology clinic. Platelet count and other platelet indices were measured in both cases and healthy controls. Erectile status of the patients was evaluated by using International Index of Erectile Function- 5 questionnaire. Results: There were 203 cases and 102 controls. The mean Index scores of the cases was 12.86±4.55 and that of the controls was 24.65±3.25 (p<0.001). Platelet levels were higher in cases than controls (p<0.001). But there was no statistically significant difference between the groups according to mean platelet volume values (p=0.309). Conclusion: Platelet values can be used as an early biomarker for erectile dysfunction. © 2018, Pakistan Medical Association. All rights reserved.Öğe Combination or Alone? Which one is the Best in Premature Ejaculation Treatment?(2020) Şentürk, Aykut Buğra; Yılmaz, Ali Haydar; Çakıroğlu, Basri; Yaytokgil, Muhammet; Sungur, Mustafa; Aykan, Serdar; Ekici, MusaIntroduction: To compare the effectiveness of tadalafil alone and in combination with dapoxetine in patients with premature ejaculation. Methods: In this study, 120 patients treated at the urology clinic for premature ejaculation were evaluated prospectively. IELT and IIEF forms of patients were filled before this study, and their urological examinations were performed. Patients that were being treated were divided into two groups. Patients in group 1 received only 5 mg tadalafil, whereas patients in group 2 received a combination of dapoxetine 30 mg and tadalafil 5 mg. Results: After the treatment, group 1 mean IEFF scores were 25.12±2.49, and mean IELT scores were 7.35±4.37 seconds. There was a statistically significant increase in both parameters (p<0.001). After the treatment, group 2 mean IEFF scores were 27.37±2.46, and mean IELT scores were 9.07±4.20 seconds. There was a statistically significant increase in both parameters (p<0.001). Discussion and Conclusion: Use of dapoxetine in combination with tadalafil instead of using tadalafil alone in the treatment of premature ejaculation will increase treatment success.Öğe Comparing use of lidocaine periprostatic nerve block and diclofenac suppository alone for patients undergoing transrectal ultrasound guided prostate biopsy(Polish Urological Association, 2018) Şentürk, Aykut Buğra; Yaytokgil, Muhammet; Ekici, Musa; Sarı, Sercan; Demir, Emre; Çakıroğlu, BasriIntroduction The objective of this study is to make a comparison between the effectiveness of the diclofenac suppository alone and periprostatic local anaesthesia infiltration alone to reduce the pain during a transrectal ultrasound-guided prostate biopsy procedure. Material and methods Between January 2014 and December 2015, 100 patients from two centres who were scheduled for transrectal ultrasound guided prostate biopsy (TRUS Bx) were included in the study. Patients were divided into two groups; diclofenac suppository group (Group 1) and Lidocaine group (Group 2). After the prostate biopsy, patients were requested to fill out a visual analogue scale in order to evaluate their pain level during the procedure. Results Since each group had been examined for VAS score, statistical differences were detected for VAS 0 and VAS 1. VAS 0 score was stated in 38 (71%) patients in Group 2, and in 25 (50%) patients in Group 1 (p = 0.040). VAS 1 score was stated in 9 (17%) patients in group 2 and 19 (38%) patients in Group 1 (p = 0.030). Conclusions Although statistical difference was detected at lower VAS scores (0 and 1) in favor of the lidocaine group during transrectal ultrasound guided prostate biopsies, there was not a significant difference in higher (>2) VAS scores; which was made with 100 mg of diclofenac suppository. Therefore, diclofenac suppository can be used as an alternative to periprostatic nerve block made with lidocaine. © 2018, Polish Urological Association. All rights reserved.Öğe Comparison of Cohen and Lich-Gregoir ureteral reimplantation in the surgical management of primary unilateral vesicoureteral reflux in children(Assoc Medica Brasileira, 2020) Aydın, Cemil; Akkoç, Ali; Topaktaş, Ramazan; Şentürk, Aykut Buğra; Aydın, Zeynep Banu; Ürkmez, Ahmet; Yaytokgil, MuhammetOBJECTIVE: Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Various intravesical and extravesical techniques have been described for the surgical correction of VUR. The aim of our study was to compare the results of open intravesical and extravesical procedures for unilateral primary VUR in children. METHODS: Between January 2012 and August 2018, 38 children with primary VUR who underwent open ureteral reimplantation surgery were retrospectively reviewed. The Cohen (intravesical) and the Lich-Gregoir (extravesical) approach were grouped as groups A and B, respectively. The groups were compared for age, gender, preoperative reflux grade, presence of lower urinary tract symptoms, operation time, discomfort and pain, analgesic requirements, duration of hematuria, postoperative complications, and hospital stay. All the parameters were statistically compared. RESULTS: There were 38 patients in this study. Group A had 18 patients, and group B had 20 patients. The mean operative time was significantly shorter in group B than in group A. The mean hospital stay was also shorter in group B. The urethral foley stay period was 4.7 0.9 days 2 0 days (p = 0.000), respectively, for group A and B. Macroscopic hematuria was seen in group A. The objective pain scale was worse after intravesical surgery. Analgesic requirements were higher in group A (p =0.131). CONCLUSION: Intravesical and extravesical ureteroneocystostomy methods are equally successful and feasible in the treatment of primary unilateral VUR. The Cohen technique is associated with a longer and more painful hospital stay, gross hematuria, and longer operative time, compared to the Lich-Gregoir technique.Öğe Comparison of three most frequently used alpha blocker agents in medical expulsive therapy for distal ureteral calculi, result of a retrospective observational study(PAGEPress, 2018) Şentürk, Aykut Buğra; Aydın, Cemil; Ekici, Musa; Yaytokgil, Muhammet; Akkoç, Ali; Baykam, Mehmet MuratPurpose: In this study, we compared the effects of three agents frequently used in daily life for medical expulsive therapy. Materials and methods: A total of 143 patients meeting the criteria were included in the study. Patients were divided into three homogeneous drug groups which were tamsulosin group (n:48), alfuzosin group (n:47) and silodosin group (n:48). The time of stone expulsion, analgesic needs, side effects of the medicine and endoscopic intervention needs of the patients were recorded. Results: The rate of stone expulsion was 70.8% (n:34) in tamsulosin group, 70.2% (n:33) in alfuzosin group, and 75% (n:36) in silodosin group. No significant difference was observed among the rates of stone expulsion in three groups, and the rates of stone expulsion were similar (p = 0.778). The duration of stone expulsion was significantly different in the groups (p = 0.012): the time of stone expulsion for tamsulosin was 2.33 ± 0.78 days longer than for Silodosin, indicating a significant difference. There was no significant difference between tamsulosin-alfuzosin and silodosin-alfuzosin (respectively p = 0.147, p = 0.925). Conclusions: The results of this study showed that medical expulsive therapy by using alpha blocker agents is safe and efficacious. This option must be kept in mind for patients who do not ask for surgery as the first-step treatment for eligible patients. © 2018 Edizioni Scripta Manent s.n.c. All rights reserved.Öğe Effect of venous reflux time on testosterone and semen parameters of infertile males after microscopic varicocelectomy(Wiley, 2020) Şentürk, Aykut Buğra; Çakıroğlu, Basri; Yaytokgil, Muhammet; Aydın, Cemil; Sungur, Mustafa; Akkoç, AliThis study aimed to search whether there is a link between reflux flow and hormonal profile. Data of 250 patients were retrospectively investigated. Pre-operative and 6th month semen analyses of these patients' results were compared with pre-operative and post-operative 6th month serum levels of testosterone. Based on the venous flow on pre-operative Doppler ultrasonography, patients were divided into two groups. Patients with a venous flow <= 4 s were assigned to Group 1 and those with a venous flow >4 s to Group 2. Venous reflux time cut-off was calculated as 4 s using ROC curve according to the increase in testosterone level. When venous reflux time was selected as approximately 4.0 s, ROC had 79.8% sensitivity and 72.8 specificity. The probability of a post-operative increase in testosterone is high in patients with a venous reflux time longer than 4 s.
