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Öğe Molecular structure, spectroscopy and reactivity: A collection of selected communications presented at the VIIth Inorganic Chemistry Congress - Corum (Turkey) Preface(Elsevier, 2020) Köse, Dursun Ali; Sağlam, Ertuğrul Gazi; Fausto, Rui[Abstract Not Available]Öğe Applications and impact of nanocellulose based adsorbents(Springer, 2020) Köse, Kazım; Mavlan, Miran; Youngblood, Jeffrey P.Abstract Efficient separation and removal is necessary in applications ranging from environmental remediation to the food sector. A well-designed adsorption system should meet the demands for high efficiency in a cost and time effective manner. In wastewater treatment, the ideal chemical feedstock used to synthesize the adsorbents should themselves been environmentally friendly (i.e. non-toxic) to avoid subsequent environmental issues. Nanocellulose, made of the most abundant organic biopolymer on earth, fulfills many criteria to fit the profile of a highly safe, but efficient adsorbent. A survey of the literature reveals that nanocellulose materials have a proven track record as viable alternatives as adsorbents. To summarize these recent advances, this review describes the methodologies under current use for such designs and gives a systematic overview of these technologies to promote a more focused research in the future for nanocellulose based adsorbent materialsÖğe Analytical and preparative scale separation of enantiomers of chiral drugs by chromatography and related methods(Bentham Science Publishers B.V., 2018) Gümüştaş, Mehmet; Özkan, Sibel Ayşıl; Chankvetadze, BezhanWhile the amino acids, enzymes and hormones are chiral, chirality plays significant role in the life of plants, animals, as well as the human being. Chirality of molecules is important in various industries, such as pharmaceutical, agricultural, food, electronics, etc. Chiral drugs may have different bioavailability, distribution, biotransformation and excretion, as well as quantitatively and/or qualitatively different pharmacological or toxic properties. Enantiomerically pure chiral drugs have been increasingly developed for the pharmaceutical market due to their superiority from the viewpoints of potency and safety. This is supported by the development of new methods for enantioselective production of the chiral compounds, as well as by the capability of the enantioselective analytical methods to allow a detection and quantification of minor enantiomeric impurity in the presence of another enantiomer in a large excess. The aim of the present review is to provide a short summary of the basic principles of chiral separations on an analytical and preparative scale. In addition, some selected applications for analytical techniques, such as gas chromatography, supercritical fluid chromatography, high performance liquid chromatography, capillary electrophoresis and capillary electrochromatography for the separation of enantiomers of chiral pharmaceuticals published in the last two years are also discussed. © 2018 Bentham Science Publishers.Öğe Recent progress on the sensitive detection of cardiovascular disease markers by electrochemical-based biosensors(Elsevier B.V., 2018) Karadaş Bakırhan, Nurgül; Özçelikay, Göksu; Özkan, Sibel AyşılCardiovascular disease is the most reason for deaths in all over the world. Hence, biomarkers of cardiovascular diseases are very crucial for diagnosis and management process. Biomarker detection demand is opened the important way in biosensor development field. Rapid, cheap, portable, precise, selective and sensitive biomarker sensing devices are needed at this point to detect and predict disease. A cardiac biomarker can be orderable as C-reactive protein, troponin I or T, myoglobin, tumor necrosis factor alpha, interleukin-6, interleukin-1, lipoprotein-associated phospholipase, low-density lipoprotein and myeloperoxidase. They are used for prediction of cardiovascular diseases. There are many methods for early diagnosis of cardiovascular diseases, but these have long time process and expensive devices. In recent studies, different biosensors have been developed to remove the problems in this field. Electrochemical devices and developed biosensors have many superiorities than others such as low cost, mobile, reliable, repeatable, need a little amount of solution. In this review, recent studies were presented as details for cardiovascular disease biomarkers detection using electrochemical methods. © 2018Öğe UPLC versus HPLC on drug analysis: Advantageous, applications and their validation parameters(2013) Gümüştaş, Mehmet; Kurbanoğlu, Sevinç; Uslu, Bengi; Özkan, Sibel AyşılLiquid chromatography (LC) is a separation technique used in many different areas to aid the identification and quantification of substances in various matrices. LC techniques with various detection modes have been widely used for the sensitive and selective determination of trace amounts of pharmaceutical active compounds in biological samples and their dosage forms. A completely new system design with advanced technology has been developed, called ultra high performance liquid chromatography, which has evolved from high performance liquid chromatography. The application of LC methods to drug analysis introduces a powerful tool for therapeutic drug monitoring as well as for clinical research. The advantages of short turnaround time, method reliability, method sensitivity, and drug specificity justify the use of LC techniques for various groups of the drug active compounds. This review describes some of the principles of ultra high performance liquid chromatography and high performance liquid chromatography, validation of these methods, system suitability tests for the methods, and application of methods to pharmaceutical analysis in the last 3 years. © 2013 Springer-Verlag Berlin Heidelberg.Öğe Erratum to: UPLC versus HPLC on drug analysis: advantageous, applications and their validation parameters(2013) Gümüştaş, Mehmet; Kurbanoğlu, Sevinç; Uslu, Bengi; Özkan, Sibel AyşılThe authors would like to call the reader’s attention to the fact that unfortunately there were several references faultily assigned in Table 1.
