Kose, KazimMavlan, MiranUzun, LokmanYoungblood, Jeffry P.2021-11-012021-11-0120210969-02391572-882Xhttps://doi.org/10.1007/s10570-020-03534-7https://hdl.handle.net/11491/7472Glycidyl methacrylate (GMA) was grafted to cellulose nanocrystals (CNCs) using hydroquinone resulting in a crosslinkable nanoparticle. 2-Hydroxyethyl methacrylate (HEMA) was used to polymerize this nanoparticle to obtain a polymeric structure with a bridging CNC structure to which cyclodextrin (CD) was attached in order to better capture hydrophobic biomolecules. X-Ray Microscopy and nuclear magnetic resonance methods provided the main characterization data proving the successful modification process. This CD-modified nanocomposite adsorbent was used for the removal of cholesterol and low-density lipoprotein for the first time. Adsorption performance in a continuous system was similar to 99% for both cholesterol and low-density lipoprotein with agreement between experimental data and mathematical models performed. Overall, results indicate that cyclodextrin modified poly(HEMA-GMA-g-CNC) is a promising material for use as an adsorbent for biological and biomedical applications.eninfo:eu-repo/semantics/closedAccessCellulose nanomaterialCyclodextrinCholesterolLow density lipoproteinRemovalArticle28147148710.1007/s10570-020-03534-7Q1WOS:0005857541000022-s2.0-85095433184Q1