Köse, Dursun AliZümreoğlu Karan, Birgül2019-05-132019-05-132012Köse, D. A., Zümreoğlu Karan, B. (2012). Mixed-ligand complexes of boric acid with organic biomolecules. Chemical Papers, 66(1), 54-60.0366-6352https://doi.org/10.2478/s11696-011-0108-0https://hdl.handle.net/11491/906Boric acid forms meta-stable complexes with biomolecules like amino and hydroxy acids and stable complexes with the diol group containing carbohydrates, vitamins, and nucleotides, yielding mono-chelate (1: 1 complex) or bis-chelate (1: 2 complex) structures with negatively charged tetrahedral borate anions. Here we report water-soluble, bio-available mixed-ligand boron adducts for potential nutritional and/or pharmaceutical applications. The complexes were prepared by complete esterification of boric acid with a number of acyclic- and cyclic hydroxy-functionalized biomolecules employing sodium as the counter ion. Structural and thermal properties of the complexes were investigated using chemical analysis, 11B NMR, FTIR, and TGA-DTA techniques. Complexes containing salicylic acid as one of the ligands displayed higher thermal and hydrolytic stabilities. © 2011 Institute of Chemistry, Slovak Academy of Sciences.eninfo:eu-repo/semantics/closedAccess11B NMRBorate EstersBoric Acid ComplexesBoron AdductsMixed Ligand ComplexesArticle661546010.2478/s11696-011-0108-0N/AQ2