Şentürk, Aykut BuğraEkici, MusaAydın, CemilBaykam, Mehmet MuratTaş, TuncayArda, ErsanÇakıroğlu, Basri2021-11-012021-11-012019Musa Ekici, M. D., Cemil Aydın, M. D., & Ersan Arda, M. D. (2019). Predicting Lamina Propria Invasion in Patients with Non-muscle-invasive Bladder Cancer: Do RDW and NLR Really Work?. Bull Urooncol, 18, 6-9.2147-21222147-2270https://doi.org10.4274/uob.galenos.2018.1099https://app.trdizin.gov.tr/makale/TXpZME1qUTVPUT09https://hdl.handle.net/11491/7574Objective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting lamina propria invasion in bladder cancer. Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were divided into those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocyte counts and RDW values were evaluated. Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease. RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4% probability of Ta disease. Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW can help clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.eninfo:eu-repo/semantics/openAccessBladder cancerSuperficialLamina propriaInvasionArticle1816910.4274/uob.galenos.2018.1099N/AWOS:000464095200002