Türk, MustafaTamer, UğurAlver, ErolÇiftçi, HakanMetin, Ayşegül ÜlküKarahan, Siyami2019-05-132019-05-132013Türk, M., Tamer, U., Alver, E., Çiftçi, H., Metin, A. Ü., Karahan, S. (2013). Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts. Artificial Cells, Nanomedicine and Biotechnology, 41(6), 395-401.2169-1401https://doi.org/10.3109/21691401.2012.761228https://hdl.handle.net/11491/1860The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929- fibroblasts. L929- fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity. © 2013 Informa Healthcare USA, Inc.eninfo:eu-repo/semantics/closedAccessChitosanCytotoxicityGold NanorodL929- FibroblastsArticle41639540110.3109/21691401.2012.761228N/AQ1