Selçuk, İlkerKorkmaz, ElmasÖzgü, EmreMengü, TürkerErkaya, SalimGüngör, Tayfun2019-05-132019-05-132015Selçuk, İ., Korkmaz, E., Özgü, E., Mengü, T., Erkaya, S., Güngör, T. (2015). Lympho-vascular space invasion indicates advanced disease for uterine papillary serous tumors arising from polyps. Asian Pacific Journal of Cancer Prevention, 16(10), 4257-4260.1513-7368https://doi.org/10.7314/APJCP.2015.16.10.4257https://hdl.handle.net/11491/1583Background: Uterine papillary serous tumors are rarely seen and behave aggressively. Our aim was to evaluate uterine papillary serous tumors arising from polyps. Materials and Methods: Clinicopathological data of patients with uterine serous cancer arising from a polyp at the Gynecological Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: We analyzed patients according to FIGO 2009 staging system as stage 1A and higher than stage 1A (3 and 6, respectively). All the patients were postmenopausal. Mean CA-125, CA-19.9 and CA15.3 levels were elevated in higher than stage 1A group. However we did not find a statistical difference between age, parity, polyp size, CA-125, CA-15.3, CA-19.9 and CEA levels. Lympho-vascular space invasion (LVSI) showed predictivity for advanced disease (p=0.025). Conclusions: The histopathologic nature of uterine serous carcinoma is a unique entity. LVSI is a prognosticator for defining an advanced stage uterine papillary tumor.eninfo:eu-repo/semantics/openAccessLVSIMyometrialPolypSerousUterine CancerArticle16104257426010.7314/APJCP.2015.16.10.4257Q3