Comba, CihanComba, AtakanYilmaz, HakanErdogan, Sakir V.Demir, Omer2021-11-012021-11-0120200932-00671432-0711https://doi.org/10.1007/s00404-020-05666-4https://hdl.handle.net/11491/7153Purpose The aim of the study was to determine whether celiac disease affects ovarian reserve assessed by antral follicle counting, ovarian volume, and anti-mullerian hormone in adolescent patients. Methods This case-control multicenter trial was performed from January 1, 2017 to May 31, 2018 and included 45 girls. On days 2-5 of the menstrual cycle, measurements of serum follicle stimulating hormone, luteinizing hormone, estradiol, prolactin, and anti-mullerian hormone were performed. Antral follicle counts and ovarian volumes were determined on the same day. Results Evaluation was made of 21 (47.7%) celiac patients with a mean age of 15.8 +/- 1.3 years, and 24 (52.3%) healthy control subjects with a mean age of 16.2 +/- 1.2. There was no difference between the groups in respect of right and left ovarian volumes (p = 0.790 andp = 0.670, respectively). Serum levels of anti-mullerian hormone of the celiac patients and controls were found comparable [(3.7 +/- 2.9 (0.5-12) and 3.6 +/- 1.8 (1.2-8.1)] ng/mL, respectively,p = 0.915). Conclusions Celiac disease may not affect the ovarian reserve determined with established ovarian reserve markers including antral follicle counting, ovarian volume, and anti-mullerian hormone in adolescent patients.eninfo:eu-repo/semantics/closedAccessCeliac diseaseAnti-mullerian hormoneAdolescentFollicle stimulating hormoneAntral follicle countsArticle30251263126910.1007/s00404-020-05666-4Q3WOS:0005436816000012-s2.0-8508712581632594297Q2