Atay, EmreGüzel, Mahmut MünirAmanvermez, RamazanDemir, Muhammed TahaErenler, Ali KemalÖzgen, EmreYücel, Mehmet2019-05-102019-05-102019Atay, E., Güzel, M.M., Amanvermez, R., Demir, M.T., Erenler, A.K., Özgen, E., Yücel, M. (2019). Role of Gal-3 and H-FABP in the early diagnosis of acute coronary syndrome. Bratislavske lekarske listy, 120 (2), 124-130 .0006-9248https://doi.org/10.4149/BLL_2019_020https://hdl.handle.net/11491/482OBJECTIVES: We aimed to compare the plasma levels of biomarkers such as: serum Gal-3, H-FABP, cTnI, and CK-MB in patients, who were admitted to the emergency room with chest pain, and to determine whether these biomarkers have early diagnostic value of acute coronary syndrome (ACS). METHODS: The study was performed in 60 patients aged ? 18 years, who were admitted to emergency room. These patients were divided into 3 groups: patients with STEMI (group I, n = 20), patients with NSTEMI (group II, n = 20), and patients with USAP (group III, n = 20). Serum Gal-3, H-FABP, cTnI, and CK-MB levels were measured at admission, and at the 2nd and 4th hours. RESULTS: There were statistically significant differences between the groups in terms of Gal-3 levels at admission, and the 2nd and 4th hours (p = 0.007, p = 0.002, and p = 0.001, respectively). There were statistically significant differences between the groups in terms of H-FABP levels at admission, and the 2nd and 4th hours (p = 0.001, p = 0.003, and p = 0.003, respectively).There were statistically significant differences between the groups in terms of cTnI levels at admission, and the 2nd and 4th hours (p < 0.001, p < 0.001, and p < 0.001, respectively). CONCLUSIONS: According to the results of the study, cTnI, H-FABP, and Gal-3 are useful parameters that can be used in the early diagnosis of ACS. © AEPress s.r.o.eninfo:eu-repo/semantics/openAccessAcute Coronary SyndromesEmergency RoomGalectin 3Heart-Type Fatty Acid-binding ProteinArticle120212413010.4149/BLL_2019_020N/AQ2