Kalçık, MacitGüner, AhmetGürsoy, Mustafa OzanÖzkan, Mehmet2021-11-012021-11-012021Kalçık, M., Güner, A., Gürsoy, M. O., & Özkan, M. (2021). Challenges in the management of patients with mechanical prosthetic heart valves during pregnancy. The journal of maternal-fetal & neonatal medicine: the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 34(8), 1342-1343.1476-70581476-4954https://doi.org/10.1080/14767058.2019.1635111https://hdl.handle.net/11491/7494To the editor, We have recently read with great interest the article by Kai et al. entitled “Pregnancy managed by unfractionated heparin (UFH) after mechanical aortic valve replacement” [1]. The authors have reported the management of a pregnant patient with mechanical prosthetic valve in the aortic position. We congratulate the authors for achieving a successful outcome in such a high-risk patient for prosthetic valve thrombosis (PVT). However, we believe that the anticoagulation therapy proposed by the authors during pregnancy requires further discussion.eninfo:eu-repo/semantics/closedAccessLetter3481342134310.1080/14767058.2019.1635111N/AWOS:0004735055000012-s2.0-8506811791731221033Q1