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    Öğe
    Correlation of Ultrasonically Determined Bladder Wall Thickness and Prostatic Calcification With the Urinary, Psychosocial Dysfunction, Organ Specific, Infection and Neurological/Systemic Symptoms, and Tenderness Scoring System
    (Elsevier Inc., 2019) Arda, Ersan; Çakıroğlu, Basri; Akdeniz, Esra; Akdere, Hakan; Yüksel, İlkan; Şentürk, Aykut Buğra
    Objective: To evaluate ultrasonically determined bladder wall thickness (BWT) and prostatic calcification presence, in men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and to correlate the findings with patient characteristics and the urinary, psychosocial dysfunction, organ specific, infection and neurological/systemic symptoms, and tenderness (UPOINT) classification system. Material and Methods: Between January 2008 and December 2017, data of 1294 patients diagnosed with chronic prostatitis, in a single urology clinic, meeting a number of selective inclusion/exclusion criteria, were retrospectively analyzed. Patients, compliant to fill out all requested questionnaires, between the ages of 21-65 years were included to the study. Exclusion criteria were noncompliance of filling out required questionnaires, acute and/or chronic bacterial prostatitis, history of genitourinary cancer, history of recent prostate surgery, and diagnosis of neurological diseases affecting the bladder. Results: The median patient age and UPOINT subdomain was determined as 37 (IQR = 13, range 21-65) and 2 (IQR = 1, range 0-5), respectively. Median values for BWT, National Institute of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), and International Index of Erectile Function were 3 (IQR = 1, range 2-6, 7), 4 (IQR = 6, range 1-23), and 25 (IQR = 10, range 1-30), respectively. The presence of calcification demonstrated a significant association with total NIH-CPSI score and BWT, whereas its relation with age and total UPOINT score was insignificant. However in contrast to calcification status, BWT >=3.3 showed a strong and statistically significant relation to all the described measurements. Conclusion: Measurement of BWT can be used as an accessible and objective method for the diagnose of CP/CPPS according to UPOINT scoring system. © 2018 Elsevier Inc.
  • [ X ]
    Öğe
    Mikroskopik varikoselektominin infertil erkeklerin gonadal hormonlar ve semen parametreleri üzerine etkisi
    (2018) Şentürk, Aykut Buğra; Çakıroğlu, Basri; Arda, Ersan
    Amaç: İnfertilite kliniğine başvuran infertil erkeklere uygulanan, subinguinal mikro varikoselektominin, cinsiyet hormonları üzerindeki etkisini değerlendirmek. Yöntem: Ocak 2014 ile Haziran 2016 tarihleri arasında, en az bir yıldır korunmasız cinsel ilişkiye rağmen, hiç çocuğu olmayan, birincil infertil hastalar çalışmaya dahil edildi. Çalışma kriterlerine uyan, 76 hastanın, folikül uyarıcı hormon, luteinize edici hormon, total testosteron düzeyleri, semen analizi ve skrotal Doppler ultrasonografi sonuçları retrospektif olarak değerlendirildi. Bulgular: Ortalama infertilite süresi 3.6 yıldı (1.5-6.3). Ameliyattan önce ve altı ay sonraki toplam testosteron değerleri sırasıyla 380 (340-465) ve 385 (350-470) idi. Bu istatistiksel olarak anlamlıydı (p <0.001). Bu artış, LH düzeylerinin 6.59 ± 1.37’den 6.79 ± 0.94’e çıkması ile koreleydi ve bu da istatistiksel olarak anlamlı bulundu (p <0,019). Sonuç: İnfertilite ve varikosel genellikle ağrı ve infertilite açısından değerlendirilmekle birlikte, cerrahi sonrası serum testosteron düzeylerinde anlamlı bir artış olması nedeniyle, düşük serum testosteron düzeyi olan hastaların ayırıcı tanısında varikosel düşünülmelidir.
  • Küçük Resim
    Öğe
    Predicting Lamina Propria Invasion in Patients with Nonmuscle-invasive Bladder Cancer: Do RDW and NLR Really Work?
    (2019) Şentürk, Aykut Buğra; Ekici, Musa; Aydın, Cemil; Baykam, Mehmet Murat; Taş, Tuncay; Arda, Ersan; Çakıroğlu, Basri
    Objective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting lamina propria invasion in bladder cancer. Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were divided into those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocyte counts and RDW values were evaluated. Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease. RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4% probability of Ta disease. Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW can help clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.